Clinical Research

Completed project

Lao Lixing

Project Period: 2013/2014 to 2017

  • Research Methodology Guideline for Acupuncture Randomized Controlled Trial

    In the past few decades, increasing number of clinical studies were conducted to evaluate the safety and efficacy of acupuncture for various diseases/conditions, using the gold standard research design of randomized controlled trial (RCT). Because of the nature of acupuncture practice, designing a high quality RCT with rigorous scientific methodology remains challenging. This guideline aim to inform scientific methodology on acupuncture research, particularly on choosing the control treatment in acupuncture RCTs.

Lao Lixing

Project Period: 2013/2014 to 2017

  • Development of Chinese Medicine Acupuncture Clinical Practice Guideline in Low Back Pain

    This project was conducted to develop clinical practice guidelines on acupuncture treating low back pain in Hong Kong. The guidelines development committee consists of 11 members who are acupuncture experts, clinical researchers, and experts in evidence-based medicine. The composition process included a plethora of research methods, such as systematic review, text mining, experts’ opinions, and consensus of local registered acupuncturists. The Delphi method was used to investigate the applicability of the CPGs. The evidence-grading system for traditional Chinese medicine (TCM) research established was adopted.

Feng Yibin

Project Period: 1 Jan 2013 - 31 December 2018

  • The role of Chinese Medicines on Tumour Associated Macrophages in Hepatocellular Carcinoma

Li Lei

Project Period: 1 April 2014 - 31 March 2016

  • A Study on Effects of Acupressure among the Frail Elderly in the Social Centers for the elderly and Neighbourhood Elderly Centers of Yan Chai Hospital, Social Services Department (YCHSS)

Zhang Yanbo

Project Period: 15 May 2014 - 14 May 2016

  • A double-blinded, randomized, two-dose trial of Tumor-shrinking Decoction (TSD), a Chinese medicine preparation in patients with symptomatic uterine fibroids

Feng Yibin

Project Period: 1 January 2015 - 31 December 2016

  • The Therapeutic Potential of Chinese Medicine on Experimental Acute and Chronic Liver Diseases

Li Lei

Project Period: 31 March 2015 - 31 March 2017

  • A Clinical Study of Thumbtack Intra-dermal Needle Therapy on Common Orthopedic Pain Syndromes

Li Lei

Project Period: 1 April 2015 - 31 December 2016

  • Efficacy Observation on Tian Jiu Therapy for Asthma

Chen Haiyong

Project Period: 1 April 2015 - 1 July 2017

  • Acupuncture on Post-Stroke Overactive Bladder: a randomized controlled trial

Wu Junmei

Project Period: 26 June 2015 - 26 December 2016

  • Activation on Left Dorsolateral Prefrontal Cortex (LDPC) with Different Acupoint-Combinations for depression: An fNIRS Study

Chen Haiyong

Project Period: 16 March 2016 – 30 September 2018

  • Sinew acupuncture on knee osteoarthritis: a randomized controlled trial

Lao Lixing

Project Period: 1 Jul 2016 - 1 July 2017

  • Combined Electroacupuncture and Auricular Acupuncture for Postoperative Pain after Abdominal Surgery for Gynecological Diseases: A Randomized Sham-controlled Trial

IRB's approval and Endorsement at Clinical Research Meeting

Lao Lixing

Project Period: 1 Jul 2016 - 30 June 2018

  • A Randomized, Wait-list Controlled Trial of Self-administered Acupressure for Symptom Management Among Chinese Family Caregivers with Caregiver Stress

    Objective:
    To evaluate the effect of a self-administered acupressure intervention on caregiver stress, symptoms of fatigue, insomnia, depression, and health-related quality of life among Chinese family caregivers of elderly family members.
    Design:
    This is a randomized, wait-list controlled trial with intervention and wait-list control groups. 200 Chinese family caregivers will be recruited. A self-administered acupressure intervention, which comprises of group learning and self-practice, total 30 hours over a period of 8 weeks is being implemented.
    Outcome measures:
    Chinese version of the Caregiver Burden Inventory, Piper Fatigue Scale, Pittsburgh Sleep Quality Index, Patient Health Questionnaire, SF-12 Health Survey, and demographic questionnaire are being used.

IRB's approval and Endorsement at Clinical Research Meeting

On-going project

Lao Lixing

Project Period: December 1, 2018 to December 31, 2019

  • The Effect of Acupuncture for Insomnia in Breast Cancer Patients Undergoing Chemotherapy: A Randomized, Wait-list Controlled Pilot Study

    Objective:
    To evaluate the therapeutic effects of acupuncture for insomnia in breast cancer patients who undergo chemotherapy.
    Design:
    This is a randomized, wait-list controlled trial with intervention and wait-list control groups. Thirty eligible subjects will receive acupuncture treatment twice per week for 6 weeks (12 sessions in total).
    Outcome Measures:
    Insomnia Severity Index (ISI), actiwatch, sleep diary, Pittsburgh Sleep Quality Index (PSQI), Hospital Anxiety and Depression Scale (HADS), Functional Assessment of Cancer Therapy-Breast Cancer (FACT-B), 5-level EQ-5D (EQ-5D-5L), reasons for withdrawal, and adverse events.

    We would like to invite you to participate in our research! Please check the poster for further information.

Lao Lixing

Project Period: 3 Mar 2016 - Ongoing

  • Electroacupuncture for Relieving Pain in Ankylosing Spondylitis: a Single-arm Pilot Study

    Objective:
    To explore the treatment effect of electroacupuncture for relieving pain in ankylosing spondylitis.
    Design:
    This is a single arm pilot study. Twenty eligible subjects will receive electroacupuncture treatment twice per week for at least 6 weeks (12 sessions in total). The length of treatment can be extended to a maximum of 10 weeks (20 sessions in total) when necessary.
    Outcome Measures:
    Pain Severity Numerical Rating Scale (NRS), Drug diary, Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Global Index (BASGI), SF-36, Bath Ankylosing spondylitis Metrology Index (BASMI), Chest expansion, Joints count, C-reactive protein (CRP), Erythrocyte sedimentation rate (ESR), Reasons for withdrawal, Adverse events, Credibility of Treatment Rating Scale (CTRS).

IRB's approval and Endorsement at Clinical Research Meeting

Li Lei

Project Period: 31 December 2016 - 31 December 2019

  • Efficacy Observation on Tian Jiu Therapy for Asthma

Li Lei

Project Period: 31 March 2017 - 31 March 2019

  • A Clinical Study of Thumbtack Intra-dermal Needle Therapy on Common Orthopedic Pain Syndromes

Chen Haiyong

Project Period: 1 June 2017-31 May 2019

  • Acupuncture on de Quervain’s Tenosynovitis: A randomized subject- and assessor-blind controlled trial

Zhang Yanbo

Project Period: 18 Jul 2017 - 17 Jul 2019

  • Efficacy, safety and response predictors of adjuvant Astragalus therapy for diabetic kidney disease – an open-label randomised controlled trial with responder regression analysis

Li Lei

Project Period: 1 Sept 2017 - 31 Aug 2019

  • Effects of Massage methodology on the constipation problem among the pre-school aged children with behavioral problem in subvented services in Yan Chai Hospital Social Services Department

Lao Lixing

Project Period: 1 Jun 2018 - Ongoing

  • Development of a Novel Auriculotherapy Device for Pain Management

    Objective:
    To develop a novel autonomic auriculotherapy device.
    Design
    This study will firstly develop an autonomic auriculotherapy device consisting of 3 basic components: a sensing and stimulation pad with an array of bi-directional sensors and stimulators, a fixture to hold the sensors on the ear, and a treatment control unit with sensing signal processing circuits and stimulation signal driving circuits. Following device onstruction, it will be tested for diagnostic accuracy and treatment effect for pain conditions in human subjects in a feasibility study.
    Outcome Measures:
    The diagnostic accuracy including specificity and sensitivity; Pain scores measured using visual analogue scale (VAS); The correlation of the auricular point detected by the device with the body pain; device use comfortability questionnaire; and possible adverse effects.

     

    We would like to invite you to participate in our research! Please check our posters for further information.