Facilities and Equipment

The laboratory occupies an area of 4,000 square ft. and is subdivided into 10 functional units as follows:

Chinese Medicine Extraction Unit

In Chinese Medicine Extraction Unit, a variety of bioactive chemical compounds are extracted and purified depending on chemical properties through solvent extraction, concentration or lyophilization, with the aids of rotary evaporators and freeze dryer.

Teaching Unit

Full-time students and postgraduate students use various instruments in the teaching area to conduct teaching experiments. The experiments include extraction and concentration of Chinese medicine constituents, as well as the chemical quantitative analysis.

Chinese Medicine Analytical Unit

Using the Ultra-High Performance Liquid Chromatography to analyse the bioactive constituents found in Chinese Medicine.

Blood Chemistry Analyzer Unit

Researchers use blood chemistry analysers to measure metabolites, electrolytes, and proteins in the blood. The experimental results will be compared and analyzed with the results of animal models or cell culture experiments to provide information about kidney, heart, liver function, and toxicology.

Tissue & Cell Culture Unit

Numerous well-established mammalian cell lines are routinely maintained for the purpose of satisfying different cellular restraints specified and required by the various kinds of Chinese medicine modulated biomedical investigations.

Histological Unit

Histological studies on pathological relief after Chinese medicine treatments of animal tissues can be carried out by routinely H&E staining and application of Immunohistochemistry (IHC) or fluorescence in situ hybridization technology (FISH).

DNA Analytical Unit

CM stimulated up- or down-regulation of gene expression can be analysed by conducting a series of experiments ranging from RT-PCR, Real-time PCR and DNA microarray for routine quantitative analysis of gene expression to high-throughput gene expression study.

Fluorescent Imaging Unit

A robust and sophisticated fluorescence imaging system empowered with a fully automatic wavelength selecting disc, computerized image focusing control and imaging capture system is used for various research studies such as investigation of the Chinese medicine modulated cellular proliferative, mitogenetic and apoptotic signalling pathways.

Protein Analytical Unit

During the transitional period of post-genomic and proteomic era, attempts to a successful extraction and purify native proteins can be repeatedly carried out by our state-of-the-art AKTAexplorer Fast Protein Liquid Chromatography System. It is powered with several sets of computer-controlled sampling and column eluting valves to allow large-scale of herbal or recombinant protein isolation and purification that is multi-dimensionally interlaced with technologies comprising ion-exchange chromatography, size-exclusion and hydrophobic interaction.

Animal Operating Theatre

For an in vitro mechanistic investigation of Chinese medicine in the treatment of disease, a variety of animal models is developed for simulating the diseases of stroke, depression obesity and liver cancer found in humans.