You are welcome to attend the Seminar. Please find the details below:

Date: July 2, 2024 (Tue)
Time: 4:00 - 6:00pm (Registration starts at 4:00pm)
Venue: Lecture Theatre 2, 1/F, HKUMed Academic Building, 3 Sassoon Road, Pokfulam, Hong Kong
Mode: Face to face
Fee: ：Free of Charge
Language: English
CME Points for RCMPs: 2 points
Enquires: Tel: 81000538；Email: scmevent@hku.hk
Registration: HERE

Speaker:
Professor Dayue Darrel Duan
Distinguished Professor, Nanjing University of Chinese Medicine
Chair Professor, College of Traditional Chinese Medicine, Hunan University of Chinese Medicine
Director, Center for Phenomics of Traditional Chinese Medicine (TCM) of Southwest Medical University
Emeritus Professor, University of Nevada Reno School of Medicine, USA

Moderator:
Professor Jiangang Shen
Professor, School of Chinese Medicine, HKU

Abstract:

Recent rapid advance in biomedical research at the “omic” levels has revealed the mismatched relationships between the genomic variabilities and the current phenotype-based definition of disease. Precision medicine was proposed in 2011 to build a new knowledge network for biomedical research and taxonomy of disease. Although the importance of phenomics and phenome-wide associated study (PheWAS) in providing new evidence and insights for precision medicine has been recognized, modern medicine lacks the scientific theories and clinical evidence to identify clinical phenomes. By contrast, abnormal and diseased conditions are defined as Zheng-hou (證候) in traditional Chinese medicine (TCM). Zheng-hou is compatible with the concept of clinical phenome. The treatment of Zheng-hou uses a corresponding Fu-fang, a unique TCM formula usually composed of several herbs. The composition of Fu-fang is based on the principles of clinical practice under the guidelines of “Bian-zheng-lun-zhi” (辨證論治), which is the early clinical practice of clinical phenomics and pharmacophenomics. Here we will introduce the emerging phenomics and pharmacophenophenics as a new paradigm for systematically understanding the principles and molecular mechanisms of TCM, which may lay a theoretical and evidence-based medical foundation not only for the modernization of TCM, but also for the digital medicine and precision medicine.

About the Speaker:

Professor Duan is an established cardiovascular pharmacologist and a pioneer of phenomics of chloride ion channels, pharmacophenomics and phenomics of TCM. He has published >100 original research articles and reviews in top scientific journals, including Nature, Physiol Rev, Circulation, Circ Res, STTT etc. He is the Executive Editor-in-Chief of Digital Chinese Medicine, Associate Editor of Acta Pharmacologica Sinica, and Pharmacological Research Modern Chinese Medicine. He is an expert reviewer for NIH, AHA, Canadian Institutes of Health Research (CIHR), the Research Grants Council (RGC) of Hong Kong, the National Natural Science Foundation of China, the Selection Committee of "Qihuang Scholars" the State Administration of TCM and the review committee of the “Chief Scientists of the Qihuang Projects ”, “the Chinese Medicine Innovation Team”, the “Young Qihuang Scholars” and "Qihuang Scholars". He is the Founder of the Academy of Cardiovascular Research Excellence (ACRE); Vice president of the Clinical Data Surveillance, the Computational Chinese Medicine, and the Network Pharmacology Committee of the World Federation of Chinese Medicine Societies.