Teaching Staff
School of Chinese Medicine,
Li Ka Shing Faculty of Medicine,
The University of Hong Kong
- (852) 3917 6479
- (852) 2872 5476
- abchen@hku.hk
Mandarin, Cantonese and English
Chinese and English
Teaching : Prescription of Traditional Chinese Medicine and Life Cultivation and Health Care
Research : Chinese Medicine and Breast disease
1996 | Doctoral Degree, Chengdu University of TCM |
1990 | Master Degree, Chengdu University of TCM |
1984 | Bachelor Degree, Chengdu University of TCM |
Dr. Chen is a highly experienced professional who has dedicated her career to teaching, clinical services, and scientific research in Chinese medicine. She is enthusiastic about teaching Chinese medicine prescriptions and Chinese medicine health preservation. Her clinical service includes gynecology, gynecological tumors, and breast cancer.
Besides, she focuses on the research on breast diseases related to liver disease and the relevant development of new Chinese medicines.
2020 - present | Principal Lecturer, School of Chinese Medicine, The University of Hong Kong |
2013 - 2020 | Associate Professor, School of Chinese Medicine, The University of Hong Kong |
2002 - 2012 | Assistant Professor, School of Chinese Medicine, The University of Hong Kong |
2001 - 2002 | Assistant Professor, Division of Chinese Medicine, HKU School of Professional and Continuting Education, HKU |
2001 - 2001 | Visiting Professor, Brown University, USA |
1998 - 2001 | Associate Professor, Sun Yat-sen University, Guanghzhou, China |
1996 - 1998 | Post-doctoral Fellow, Sun Yat-sen University, Guangzhou, China |
1990 - 1993 | Attending Physician, Chengdu University of Traditional Chinese Medicine, Chengdu, China |
1984 - 1987 | Resident Physician, Chengdu University of Traditional Chinese Medicine, Chengdu, China |
Research Interest
- 1. Experimental research (實驗研究)
- a) Developing Chinese medicine drug such as normal drug & nanoparticles and nanofiber medicine for cancer therapy; Developing TCM drug for decrease side effect of chemotherapy drugs & anticancer (Nano-CM)
- b) Improving Cancer-Microenvironment; discovering mechanisms of herbal medicine to promote chemo-synergism and chemo-sensitization.
- c) Developing TCM thesis for breast disease
- 2. Clinical research (臨床研究)
- a) The effect of constitution on the onset of breast cancer (體質影響乳癌的發生與變化)
- b) Effect of dietary foods on chemotherapy-induced toxicity in cancer patients
Research Grant
1) External (PI)
- The novel oral administration isoliquiritigenin-protein/albumin Nano drug targeting for triple-negative breast cancer treatment (ITF MRP/027/18X on going HK$:5,000,000). 2020-2023
- Study on key technology of caulis Spatholobi industrialization. Guangxi Science and Technology Key Research and Development Program (No. AB16450012:important international cooperation fund) RMB 27,000,000(finish stage I 2017-2023), PI.
- Development of tea bag YH0618, an herbal dietary supplement against chemotherapy-induced toxicity (ITF UIM/2762015-2017) IHK$ 927,521.00
- Development of Tea Bag YH0618, an Herbal Dietary Supplement against Chemotherapy-induced Toxicity. nP/276/15 HK$: 89, 796.45 2015-2017
- The inhibition effect Suberect Spatholobus on the migration of breast cancer via Wnt/β-catenin pathway induced by miRNA NSFC (National Natural Science Foundation of China), No. 81573663 PI 2016-2019.
- Metabolomics analysis of endogenous metabolites in breast cancer cells exposed to polybrominated diphenyl ethers (HK$ 483,065) 2014. GRF No 12300114(co-i2014-2016).
- Exploration of dietary compound isoliquiritigenin in chemosensitizing breast cancer stem cells by targeting aberrant β-catenin signaling. (HMRF approved 2013)
- A double-blinded, randomized, two-dose trial of Tumor-shrinking Decoction (TSD), a Chinese medicine preparation in patients with symptomatic uterine fibroids (HMRF approved 2013 No: 11121841)
- A kind of the Spatholobus mendicant inhibit LDH-A and Mechanism of anti-breast cancer. (亞熱帶密花豆屬藥用植物 LDH-A 抑制劑的發現及其抗乳腺癌分子機制研究). (Guangdong-HK collaboration /NSFG fund 2012B050300014 as PI)
- ITF: Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A (HK$M: 1.25, 2011/13, No. ITS-073-11FP.as PI).
- 黄山药抗心肌缺血作用机制研究NSFC 2003-2006 (No 303701761) (24,0000, as PI).
2) Internal
- Development of a novel nano Chinese drug (NS-SS-ISL) base on a smart design (natural nano self-assembly material loaded ISL) for breast cancer treatment and prevention. Seed funding (applied) HK$ 90,100. 2015.
- Elucidating the critical role of GRP78 in breast cancer chemoprevention by targeting the aberrant Wntβ-catenin signaling in cancer stem cells. Seed funding (basic) HK$ 43,000. 2015.
- Elucidating anti-angiogenesis effects of Isoliquiritigenin by attenuating endothelial differentiation potential of breast cancer stem cells via Wntβ-catenin signaling Seed funding (basic) HK$ 49,625. 2015.
- A novel nanoparticle PBCA-PEG-DOX-ISL target on MDR breast cancer by connecting nanocarrier system and drug combinations. Seed funding (applied) HK$ 85,000. 2014.
- Relationships between constitutional types of traditional Chinese medicine and Breast cancer. HK$ 35,800. 2013
- Exploring cancer preventive function of a dietary compound Isoliquiritigenin by limiting breast cancer stem cells via beta-catenin/COX-2 pathway Seed funding Programme for basic research.HK$ 84,100. 2013。
- Exploring cancer preventive function of a dietary compound Isoliquiritigenin by limiting breast cancer stem cells via beta-catenin/COX-2 pathway(RCGAS0768306373)
- Elucidating Caveolin-1 as a negative regulator for breast cancer glycolysis activity via activating the c-Myc induced energy metabolism reprogramming.
- Identification and characterization of natural LDH-A inhibitor from Chinese Herbs for breast cancer prevention(RCGAS0768306369)
- Exploration of active components from Spatholobus suberectus for treating breast cancer and preventing its recurrence and metastasis (200907160015, completed).
- Inhibiting breast cancer metastasis through TGF-β1-Induced Epithelial-Mesenchymal Transition (EMT) by Isoliquiritigenin (ISL) (2012;201111159174)
- Regulation Role and Mechanisms of LDH-A on Angiogenesis and VEGF Expression in Cancer Cells (2011, 201011159142).
- Effects and Mechanisms of Litchi seed Extracts against Lung Specific Metastasis of Breast Cancer (2009, completed).
- Role of Diocin and Diosgenin in protecting myocardium ischemia through reducing cholesterol level at the membrane of red blood cell (2007 completed).
- Mechanisms of extracts of Dioscorea Panthaica Prain et Burkill in protecting cardiomyocytes from hypoxia-reoxygenation injury and regulating lipid metabolism (2004, completed).
- Experimental study of Erxian Decoction on blocking apoptosis of ovary granulosa cells in middle-aged female rats (2004 as Co-I. 200411159053 completed).
- Elucidating Caveolin-1 as a negative regulator for breast cancer glycolysis activity via activating the c-Myc induced energy metabolism reprogramming Small Project Funding. HK$ 69,575, 2013.
- Mechanism exploration of increased intracellular level of ROS in inhibiting breast cancer growth and metastasis caused by Spatholobus suberectus (200907176148).
- Investigation of the Mechanisms and Effects of Phytoestrogen from Dang-gui (Angellica sinensis) on Breast Cancer Cells (200807176115 completed).
- The effects of quickening blood circulation & transforming blood stasis on feminine tumors by Chinese herbs (DC0618, 200507176073 completed).
- Identification and characterization of natural LDH-A inhibitor from Chinese Herbs for breast cancer prevention. Seed funding programme for applied research HK$100,000, 2013.
3) Other Funding
- Cross-institutional Online PBL in Chinese Medicine Education. TDG Funding: 98,000 (2015).
- Research on the use of Multimedia Teaching in the Science of Chinese Medicine Prescriptions (2006)
- The use of multimedia in teaching Chinese Medicine (CM) prescriptions. TDG Funding: (2004).
- LKK Funding: The use of multimedia in teaching Chinese Medicine (CM) prescriptions (2005).
- LKK Funding: The development of multimedia teaching and learning system in TCM -prescription subject (201011165001)
- Donations:
- No. 200006367. Research (Professional Services Fund for Research.
- No.208040047. 4th year - MF-Identification and Characterization of Natural LDH-A Inhibitor from Chinese Herbs for Breast Cancer Prevention. HK$ 150,000
- No. 263740115 The development of multimedia teaching and learning system in TCM prescription subject. HK$ 55,000
4) External Peer-reviewed competitive research grants
National Natural Science Foundation of China. 2010-now
Guangdong National Natural Science Foundation of China. 2013
5) Evidence of excellent applied research and or Knowledge transfer
The title: A tea bag YH0618, an herbal dietary supplement against chemotherapy-induced toxicity. We have developed an innovation approach to reduce side effect of chemotherapy, which has applied patent (application) No: 2016102214254 China. Which has transferred industry (Oriental Intel Health Products Co. LTD). The product are conducting pilot pharmacological in factory. I believe it is the can obtain great economic and social effects.
6) Information to show international standing and contribution to knowledge in the field
Used dietary supplement against chemotherapy-induced toxicity. We have developed an innovation approach (foods) to reduce side effect of chemotherapy which has applied patent (application) No: 2016102214254 China.
Award
- 雞血藤的創新性研究與應用, 中国民族医药协会, 2021年中国民族医药协会科学技术奖二等奖, 2021(陈建萍; 王志宇;王冬梅;刘青青;)。
- 鸡血藤抗乳腺癌新机制、新用途和新产品的系统研究, 中国中西医结合学会, 中国中西医结合学会科学技术奖,2017(陈建萍; 王志宇; 王冬梅等) (科研奖励)
- Outstanding Teacher in Chengdu University of TCM, China, 1996.
1. Teaching to undergraduates
- More than 34 years’ as a teacher in the school of Chinese Medicine, HKU and mainland China.
- Obtained award of Outstanding Teacher in Mainland China.
- The courses have taught currently: “Chinese Medicine Prescription” ,“Life Cultivation and Healthcare of Chinese Medicine”, “Chinese Materia Medica” “ Chinese Medicine program” and so on for B Chin Med, MBBS Boarding Course; HA Certificate Programmer for Western Medicinal doctors
2. Supervision of Research Postgraduate Students
Generally, Dr.JP Chen has successfully guided several postgraduates to designing and accomplishing their essential projects. Currently, in her team, there are eight PhD and MPhil students conducting interesting proposal. Dr. Chen’s PhD and MPhil students all completed successfully completed thesis. Some of them one awarded outstanding and two awarded excellent students in HKU. There are two students has already become as full professor in Guangzhou University of TCM and Jiangxi University of TCM in mainland China. One of them awarded National Labor Medal in mainland China. My PhD students (Ms. Wang Neng & Mr. Hang Feng) two-time got the prizes of Chinese Medicine postgraduate in 2014, 2021.
3. Additional Information on Teaching Activities
- Training young teachers: give train plan and as a supervisor from 2022
- Revolution teaching way in my subjects, such as PBL, multimedia, discussion and method of examination in 2021.
- Developing teaching way of the pharmacy apprentice online in COVID-19 phase.
- Training young teachers of our school, such as guided teaching, demonstration lesson, exchange of teaching in 2020-2021
- Multimedia teaching research
- Year II Coordinator of BChinMed program 2002-2015.
- e-PBL education on Chinese Medicine prescription
- Discussion and presentation on my teaching subjects
- TCM diet practice.
- Visit to Rehabilitation hospitals.
4. Award on Teaching Activities
- Cross-institutional Online PBL in Chinese Medicine Education. TDG Funding: 102,000 (2015-2016).
- Research on the use of Multimedia Teaching in the Science of Chinese Medicine Prescriptions (2011, 2006) TDG Funding: The use of multimedia in teaching Chinese Medicine (CM) prescriptions (2004).
- LKK Funding: The use of multimedia in teaching Chinese Medicine (CM) prescriptions (2005).
- LKK Funding: The development of multimedia teaching and learning system in TCM-prescription subject (201011165001)
Women disease, special breast cancer (breast disease)
Review expert of related academic journals, review of funds (such as National Natural Science Foundation of China, Hong Kong Chinese medicine review experts, review of new drugs, consultation, etc. Currently, she is a Hong Kong scientific review expert, a new drug review expert, a National Natural Science Foundation of China review expert, and a variety of scientific journals. and Guest Editors.
相關學術論文的評審, 基金的評審( 如國家自然基金, 香港中醫藥專家, 對新葯 的評審, 諮詢等工作。目前為香港科學評審專家,新葯評審專家, 國家自然基金評審專家, 多種科學雜誌的評審專家以及特邀編輯
Board Membership
Members of International Research Bodies
- Executive Council Member, Committee of Chinese Medical Breast disease 2016 -2019.
- Executive Council Member, Committee of Specialty committee of Multidimensional Evaluation, World Federation of Chinese Medicine Society, 2015.9-2019.9.
- Executive Council Member, Committee of Chinese Medical Pharmacology, World Federation of Chinese Medicine Society, 2012.9-2016.9.
- Executive Council Member, Committee of Translation, World Federation of Chinese Medicine Society, 2012.11-2016.11Council Member.
- Standard Committee of Integrated Western and Chinese Medicine Society for Neurological Diseases, China, 2012.8-2015.7
- Excellent and Famous Overseas Professorship, Chengdu Chinese Medical University, China, 2013-2016.
- Local Organizing Committee Member for the Hong Kong traditional Chinese medicine expert for news drug evaluation.
1. Publications (https://orcid.org/0000-0001-6494-5271)
A. Books
- Chapters of Book Chinese Medicinal formula (方劑學(International 國際版2021). People’s Health Publishing House China 2021
- 陳建萍 (主編)。話說雞血藤--一味從平凡走向神奇的中藥,香港:靈蘭閣中醫藥文化有限公司2019。
- 陳建萍 (主編)《健康你話事》(中文) Ling LAN Press,2018 in HK(978-988-78558-6-6).
- The textbook “The culture of TCM” 2016 Scientific and Technical Publishers in shanghai.
- Chapters of Book “Chinese medicine Doctor in Hong Kong”2014 in HK(978-988-13247-0-2).
- Chapters of Book “The Road of Chinese medicine” to be published at the end of 2014 by people health Publishers, China
- Chapters of Book “Chinese Medicine Textbook Prescription” to be published at the end of 2012 by Shanghai Scientific and Technical Publishers, China
- Chapters of Book “Sini Decoction of Chinese Medicine” by People's Health Publishing House China(2011)
- JP Chen (Independent editor-in-chief) “Prescription of Chinese Medicine” (scholarly book, 545 pages (400,000 words) Publication in 2006, Commercial Press HK, ISBN978-962- 07-31709). (Print in 2006; Reprint in 2009,2012 and 2015).
- JP Chen (Independent editor-in-chief) “Wide Strategy of Prescription” (scholarly book, 178 pages (150,000 words) Publication in 2007, Ling LAN Press HK, ISBN 978-988-98674-6-1).
- Chapters of Book: miracle at treatment- cancer by integrating western and Chinese medicine. (PP 56-57) published at HK 2008.中西合壁愛顯奇蹟(抗癌篇宜與忌),香港,拓盛健康發展公司2008。
- Chapters of Book “International Standard English Chinese Medicine Textbook Prescription” to be published at the end of 2011 by People's Health Publishing House China.
- Chapters of Book Chinese medicine formulas “2014 by People's medical publishing House (ISBN: 978-117-19373-3.)
- Dietary Health columnist in Gourmet magazine from 2009.6-2012 (Bimonthly magazine) Health columnist in Bauhinia Health magazine since2015-2022.
- 方劑泰斗陳潮祖. Ling LAN Press HK, ISBN (978-988-98674-6-1) 2017.
B. Papers
2022
- Y Wang, C Zhang, M Xiao, Kumar Ganesan, F Gao, Q Liu, Y Sui, F Zhang, K Wei, Y Wu, Cg Xu, Y Li, P Li, J Zhang, J Chen*. A tumor-targeted delivery of oral isoliquiritigenin through encapsulated zein phosphatidylcholine hybrid nanoparticles prevents triple-negative breast cancer. Journal of Drug Delivery Science and Technology 2022. NOV. Journal of Drug Delivery Science and Technology.
- Zhen Ye,Kumar Ganesan,Mingquan Wu,Yu Hu, Yingqi She, Qianqian Tian,Qiaobo Ye Jianping Chen* Crosstalk between Depression and Breast Cancer via Hepatic Epoxide Metabolism: A Central Comorbidity Mechanism. Molecules 2022,OCT. 27(21), 7269; doi.org/10.3390/molecules27217269
- K Ganesan, B Du, J Chen*. Effects and mechanisms of dietary bioactive compounds on breast cancer prevention. Pharmacol Res. 2022 Apr;178:105974. doi: 10.1016/j.phrs.2021.105974.
- Zhang F, Ganesan K, Liu Q, Chen J. A Review of the Pharmacological Potential of Spatholobus suberectus Dunn on Cancer. Cells. 2022 Sep 15;11(18):2885. doi: 10.3390/cells11182885.
- Min Wen, Chen Qi, Wang Chen, Jing Yang, Xiao gang Zhou, Chun xiang Zhang, An guo Wu, Jia Lai, Jian ping Chen, Qi bing Mei, Shuo Yang, Cai Lan, Jian ming Wu, Fei hong Huang, Long Wang. A Comprehensive Review of Rubia cordifolia L.: Traditional uses, Phytochemistry, Pharmacological activities, and Clinical applications. Front Pharmacol. 2022 Sep 9;13:965390. doi: 10.3389/fphar.2022.965390.
- Meng Xiao, Shuyang Wu, Yanfen Cheng, Jiaqi Ma, Xi Luo, Liang Chang, Chen Zhang, Jianping Chen, Liang Zou, Yu You, Jinming Zhang. Colon-specific delivery of isoliquiritigenin by oral edible zein/caseate nanocomplex for ulcerative colitis treatment. Frontiers in Chemistry, section Nanoscience. Front Chem. 2022 Sep 9;10:981055. doi: 10.3389/fchem.2022.981055.
- F Zhang, K Ganesan, Y Li,J Chen*. In-Silico Drug Toxicity and Interaction Prediction for Plant Complexes Based on Virtual Screening and Text Mining. International Journal of Molecular Sciences. 2022 Sep 2;23(17):10056. doi: 10.3390/ijms231710056.
- An M, Xu Y, Xiao N, Huang J, Wu S, Zhuo Q, Lai Y, Chen J, Li P, Du B*. Douchi Ameliorates High-Fat Diet-Induced Hyperlipidaemia by Regulation of Intestinal Microflora in Rats. Int J Food Sci Technol. 2022 Feb; 57: 2756-2769. First published: 27 February 2022 https://doi.org/10.1111/ijfs.15655 (IF 3.612/ 3.575) Q2
- 藍紹航,李娜娜,施朝佳,黃波,陳建萍,方剛。基于數據挖掘的含雞血藤-黃芪藥對方劑的組方規律分析,中醫藥導報。01-2022 FEB;28 (1):152-155。
- Jiang J*, Xiao J, He J, Cai Z, Chen J, Yin J*. Prediction and Verification of Epimedium Flavonoids with Different Glycosylation Numbers in Reversing Glucocorticoid-Induced Bone Formation Inhibition by Molecular Docking and Zebrafish. Front Environ Sci. 2022 Feb; 9: 793527. https://doi.org/10.3389/fenvs.2021.793527 (IF 5.411/ 6.313) Q2
- Lai J, Tang Y, Yang F, Chen J, Huang FH, Yang J, Wang L, Qin D, Law BY*, Wu AG*, Wu JM*. Targeting Autophagy in Ethnomedicine against Human Diseases. J Ethnopharmacol. 2022 Jan; 282: 114516. PMID: 34487846 DOI: 10.1016/j.jep.2021.114516 (IF 5.195/ 5.242) Q2
- Li Y, Ganesan K, Chen J*. Role of Biological Mediators of Tumor-Associated Macrophages in Breast Cancer Progression. Curr Med Chem. 2022 May. (Published online before print) doi: 10.2174/0929867329666220520121711.PMID: 35619312 (IF 4.74/ 5.046) Q2
- Lin J, Wen J, Xiao N, Cai YT, Xiao J, Dai W, Chen JP, Zeng KW, Liu F, Du B*, Li P*. Anti-Diabetic and Gut Microbiota Modulation Effects of Sacha Inchi (Plukenetia volubilis L.) Leaf Extract in Streptozotocin-Induced Type 1 Diabetic Mice. J Sci Food Agric. 2022 Aug; 102 (10): 4304-4312. PMID: 35043419 DOI: 10.1002/jsfa.11782 (IF 4.125/ 4.096)
- Ng SM*, Yin MXC*, Chan JSM, Chan CHY, Fong TCT, Li A, So KF, Yuen LP, Chen JP, Chung KF, Chan CLW. Impact of Mind-Body Intervention on Proinflammatory Cytokines Interleukin 6 and 1β: A Three-Arm Randomized Controlled Trial for Persons with Sleep Disturbance and Depression. Brain Behav Immun. 2022 Jan; 99: 166-176. doi: 10.1016/j.bbi.2021.09.022 (IF 19.227/ 13.731) Q1
- Qingqing Liu,Ka-Yi Kwan,Tianyu Cao,Bingpeng Yan,Kumar Ganesan,Lei Jia,Feng Zhang,Chunyu Lim,Yaobin Wu,Yibin Feng,Zhiwei Chen,Li Liu,Jianping Chen*. Broad-spectrum antiviral activity of Spatholobus suberectus Dunn against SARS-CoV-2, SARS-CoV-1, H5N1, and other enveloped viruses. Phytotherapy Research 5 March 2022. DOI: 10.1002/ptr.7452
- Jinming Lin, Jiamin Wen, Nan Xiao, Yu-Tong Cai, Jie Xiao, Wenhao Dai, Jian-Ping Chen, Ke-Wu Zeng, Fengsong Liu, Bing Du, Pan Li. Anti-diabetic and gut microbiota modulation effects of sacha inchi (Plukenetia volubilis L.) leaf extract in streptozotocin-induced type 1 diabetic mice. First published: 19 January 2022 https://doi.org/10.1002/jsfa.11782
- Wang L, Zhang T, Liu S, Mo Q, Jiang N, Chen Q, Yang J, Han YW, Chen JP, Huang FH, Li H, Zhou J, Luo JS*, Wu JM*. Discovery of A Novel Megakaryopoiesis Enhancer, Ingenol, Promoting Thrombopoiesis through PI3K-Akt Signaling Independent of Thrombopoietin. Pharmacol Res. 2022 Mar; 177: 106096. . doi:10.1016/j.phrs.2022.106096 (IF 10.334/ 9.105) Q1
- Cong Xu,Kumar Ganesan,Xiaoyan Liu,Qiaobo Ye,Yuenshan Cheung,Dan Liu,Shaowen Zhong, and Jianping Chen* Prognostic Value of Negative Emotions on the Incidence of Breast Cancer: A Systematic Review and Meta-Analysis of 129,621 Patients with Breast Cancer. Cancers 2022, 14, 475. https://doi.org/10.3390/cancers14030475. (IF: 7.3)
- Ganesan K, Bin Du, Jianping Chen* . Effects and mechanisms of dietary bioactive compounds on breast cancer prevention. Pharmacology Res. 2021 Nov 21:105974. doi: 10.1016/j.phrs.2021.105974. PMID: 3481856. IF: 7.658
- Zhou P, Li J, Chen Q, Wang L, Yang J, Wu A, Jiang N, Liu Y, Chen J, Zou W*, Zeng J*, Wu J*. A Comprehensive Review of Genus Sanguisorba: Traditional Uses, Chemical Constituents and Medical Applications. Front Pharmacol. 2021 Sep; 12: 750165. PMID: 34616302 PMCID: PMC8488092 DOI: 10.3389/fphar.2021.750165 (IF 5.988/ 6.455) Q1
- Kumar Ganesan, Yan Wang, Fei Gao, Qingqing Liu, Chen Zhang, Peng Li, Jinming Zhang, Jianping Chen* Targeting Engineered Nanoparticles for Breast Cancer therapy. pharmaceutics 2021 Nov, ID 1394573 , Doi 10.3390/pharmaceutics13111829 (IF: 6.321)
- Ng S.M., YIN X., Chan J.S.M., Chan C.H.Y., Fong T.C.T., Li A., So K.F., Yuen L.P., Chen J., Chung K.F. and Chan C.L.W. Impact of mind–body intervention on proinflammatory cytokines interleukin 6 and 1β: A three-arm randomized controlled trial for persons with sleep disturbance and depression, Brain, Behavior, and Immunity. 2021 Oct 8;99:166-176. doi: 10.1016/j.bbi. 2021.09.022
- Feng Zhang,Qingqing Liu, Kumar Ganesan, Kewu Zeng, Jiangang Shen, Fang Gang, Xiaohe Luo , Jianping Chen*. The Antitriple Negative Breast cancer Efficacy of Spatholobus suberectus Dunn on ROS-Induced Noncanonical Inflammasome Pyroptotic Pathway. Oxidative Medicine and Cellular Longevity, Volume 2021, Article ID 5187569, 17 pages. https://doi.org/10.1155/2021/5187569. (IF 6.543, Q1)
- Ping Zhou, Jingyan Li,Qi Chen, Long Wang,Jing Yang, Anguo Wu, Nan Jiang, Yuanzhi Liu,Jianping Chen,Wenjun Zou,Jing Zeng, Jianming Wu. A Comprehensive Review of Genus Sanguisorba: Traditional Uses, Chemical Constituents and Medical Applications. Front. Pharmacol., 20 September 2021 | https://doi.org/10.3389/fphar. 2021.750165
- Hongni Zhu, Jeishu You, Yi Wen,Lei Jia , Fei Gao, Kumar Ganesan, Jianping Chen*.Tumorigenic risk of Angelica sinensis on ER-positive breast cancer growth through ER-induced stemness in vitro and in vivo. 2021 Journal of Ethnopharmacology,Volume 280, 15 November 2021, doi: 10.1016/j.jep.2021.114415. IF: 4.36
- Tao Zeng, Ting Xie, Kumar Ganesan, Fang Gang, Jianping Chen*. Targeting Eczema Treatment by Clearing the Liver Heat and Detoxification: a Clinical Case Report. Pharmacophore, 12(2) 2021, Pages: 1-5.
- Youzhi Sun, Qianjun Chen, Pei Liu1, Yi Zhao, Yanhua He, Xiao Zheng Wei Mao, Lei Jia, Kumar Ganesan, Feizhi Mo, Jianping Chen*.. Impact of Traditional Chinese Medicine Constitution on Breast Cancer Incidence: A Case-Control and Cross-Sectional Study. Pharmacophore, 12(2) 2021, June Pages: 46-56. IF: 4.36
- Yi Wen, Hansen Chen, Lu Zhang, Meiling Wu, Feng Zhang, Dan Yang, Jiangang Shen, Jianping Chen*. Glycyrrhetinic acid induces oxidative/nitrative stress and drives ferroptosis through activating NADPH oxidases and iNOS, and depriving glutathione in triple-negative breast cancer cells. Free Radic Biol Med. 2021 Jul 14;173:41-51. doi: 10.1016/j.freeradbiomed. IF: 7.36
- Lei Jia, Li Guo, Zhuanfang Zheng, Jin Yu, Jieshu You, Kumar Ganesan, Yi Lin, Jianping Chen*. Music Therapy in Traditional Chinese Medicine Attenuates the Depression-Associated Breast Cancer Development in MMTV-PyMT Mice and Clinics. International Journal of Medical Research & Health Sciences, 2021 Oct, 10(3): 110-12.
- Yue Sui, Jianming Wu, Jianping Chen*.(2021)The Role of Gut Microbial β-Glucuronidase in Estrogen Reactivation and Breast Cancer. Front. Cell Dev. Biol., 12 August 2021 | https://doi.org/10.3389/fcell.2021.631552. IF: 5.36
- Jun Jiang, Jianpeng Xiao, Jinjin He1, Zhihui Cai, Jianping Chen, Jiangning Yin. Prediction and Verification of Epimedium Flavonoids with Different Glycosylation Numbers in Reversing Glucocorticoid-Induced Bone Formation Inhibition by Molecular Docking and Zebrafish. Front. Environ. Sci., 08 February 2022 | https://doi.org/10.3389/fenvs.2021.793527
- Fu Peng, Hailin Tang, Jiaohui.Du, Jianping Chen*, Cheng Peng, (2021). Isoliquiritigenin Suppresses EMT-Induced Metastasis in Triple-Negative Breast Cancer through miR-200c/C-JUN/β-Catenin. The American Journal of Chinese Medicine, 2021 Feb 25,Vol. 49, No. 2, 505–523 DOI: 10.1142/S0192415X21500233
- Liu YC, Feng N, Li WW, Tu PF, Chen JP, Han JY*, Zeng KW*. Costunolide Plays an Anti-Neuroinflammation Role in Lipopolysaccharide-Induced BV2 Microglial Activation by Targeting Cyclin-Dependent Kinase 2. Molecules. 2020 Jun; 25 (12): E2840. (IF 3.06/ 3.38)
- Jing Guo,Yifeng Shen , Bin Li , Fei Wang , Yang Jiang , Yi Lin , Jianping Chen*. Does Tai Chi Chuan improve psychological well-being and quality of life in patients with breast cancer? Protocol for a systematic review of randomized controlled trials A Protocol for Systematic Review and Meta-Analysis. Medicine (Baltimore). 2020 Apr;99(16):e19681. PMID: 32311942,PMCID: PMC7220518,doi: 10.1097/MD.0000000000019681.
- 姜洋,刘青青,张鋒,陈建萍*;鸡血藤通过调控SNX9及β-catenin抑制三阴性乳腺癌细胞转移的作用机制.[J].中国中西医结合杂志,2020,40(11):1356-1359
- 程健珊,吳瑋,陳建萍,羅翌,蔡輝穎,石軍,榮建輝,張樟進,沈劍剛,馮奕斌* 新型冠狀病毒疾病(COVID-19)的中醫藥防治進展及展望,香港中醫雜誌.04-2020;15 (2):11-09。
- 劉鈺萍,賈雷,張鋒,文毅,曾克武,吳清華,裴瑾*,陳建萍*。不同來源雞血藤化學特征與抗腫瘤作用差異研究,中藥藥理與臨床。03-2020;36 (02):136-140。2019
- Cao ZX, Wen Y, He JL, Huang SZ, Gao F, Guo CJ, Liu QQ, Zheng SW, Gong DY, Li YZ, Zhang RQ, Chen Jianping *,Peng C*. Isoliquiritigenin, an Orally Available Natural FLT3 Inhibitor from Licorice, Exhibits Selective Anti-Acute Myeloid Leukemia Efficacy In Vitro and In Vivo. Mol Pharmacol. 2019 Nov; 96 (5): 589-599. (IF 3.853/ 3.777) Q1
- Zheng, Y., Liu, P., Wang, N., Wang, S., Yang, B., Li, M., Chen J... & Wang, Z. (2019). Betulinic acid suppresses breast cancer metastasis by targeting GRP78-mediated glycolysis and ER stress apoptotic pathway. Oxidative medicine and cellular longevity, 2019. [Cited by 15]
- Cheng IC, Li RK, Leung GP, Li SL, Kong M, Lao LX, Zhang ZJ, Lin WL, Ng EH, Rong JH, Chen JP, Su J, Zhang KY*, Meng W. Application of UPLC-MS/MS to Simultaneously Detect Four Bioactive Compounds in the Tumour-Shrinking Decoction (FM1523) for Uterine Fibroids Treatment. Phytochem Anal. 2019 Jul; 30 (4): 447-455. (IF 1.963/ 2.31) Q2
- Liu Q, Peng F, Chen J*. The Role of Exosomal MicroRNAs in the Tumor Microenvironment of Breast Cancer. Int J Mol Sci. 2019 Aug; 20 (16): E3884. (IF 4.183/ 4.331) Q2
- You JS, Guo L, Huang M, Shi XL, Lin MD, Guo Z, Cao YL, Sun YZ, Xu Q, Qu WL, Liu HL, Chen JP*. The Effect and Mechanism of YH0618 Granule on Chemotherapy- Induced Hair Loss in Patients with Breast Cancer: Study Protocol for a Randomized, Double-Blind, Multi-Center Clinical Trial. Trials. 2019 Dec; 20 (1): 719. (IF 1.975/ 2.258) Q3.
- 陳建萍*,司徒紅林,陳前軍,王志宇,主審林毅。林毅教授巧用中醫外治法防治乳腺病,香港中醫雜誌。10-2019;14 (4):20-23。
- YF Zheng PX Liu, N Wang, SQ Wang, BW Yang, M Li, JP Chen, HL Situ, MQ Xie, Y Lin, ZY Wang. Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway. Oxidative Medicine and Cellular Longevity Volume 2019, ID 8781690 (IF: 4.868, Rank: 56/193, Q2, co-author)
- Issac CC Cheng, RK Li, George PH Leung, SL Li, M Kong, LX Lao, ZJ Zhang, WL Lin, Ernest HY Ng, JH Rong, JP Chen, JS, Kalin YB Zhang, W Meng. Application of UPLC‐MS/MS to simultaneously detect four bioactive compounds in the tumour‐shrinking decoction (FM1523) for uterine fibroids treatment. Phytochemical Analysis. 2019 Jul; 30(4): 447-455. doi: 10.1002/pca.2827. Epub 2019 Mar 27. (IF: 1.963)
- JS You, F Gao, HL Tang, F Peng, L Jia, K Huang, KL Chow JQ Zhao, HL Liu, Y Lin, JP Chen*. A medicinal and edible formula YH0618 ameliorates the toxicity induced by Doxorubicin via regulating the expression of Bax/Bcl-2 and FOXO4. Journal of cancer 2019; 10(16): 3665-3677. doi: 10.7150/jca.32754 (IF: 3.182, Rank: 105/230, Q2, corresponding author)
- 王能,張奉學,陳建萍,向松濤,司徒紅林,林毅,王志宇。中醫藥干預惡性腫瘤轉移新模式—靶向調控預轉移,環球中醫藥. 03-2019; 12 (03): 464-469.
- Weiye HU, Chen J, You J, Huang M, Guo L, Lin Y. Treatment of Breast Cancer by Internal and External Chinese Medicine Combination Therapy: An Effective Case Report of Traditional Chinese Medicine Treatment Clinics in Oncology 2019; 4: 1658.
- Zheng Y, Liu P, Wang N, Wang S, Yang B, Li M, Chen J, Situ H, Xie M, Lin Y,Wang Z. Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway. Oxid Med Cell Longev. 2019 Aug 19; 2019:8781690. doi: 10.1155/2019/8781690., Q1).
- YZ Sun, Y Zhao, Steve A Xue, JP Chen*. The theory development of traditional Chinese medicine constitution: a review. Journal of Traditional Chinese Medical Sciences (2018)5, 16-28.
- SX Wang, KS Liu, YF Lou, SQ Wang, YB Peng, JP Chen, JH Huang, SX Xie, L Cui, X Wang. RNase H Meets Molecular Beacons: An Ultrasensitive Fluorometric Assay for Nucleic Acids. Microchimica Acta. 2018 Jul; 185 (8): 375. doi:10.1007/s00604-018-2909-0. (IF: 5.479, Rank: 9/84, Q1 )
- ZY Wang, N Wang, XY Liu, Q Wang, B Xu, PX Liu, HY Zhu, JP Chen, HL Situ, Y Lin. Broadleaf Mahonia Attenuates Granulomatous Lobular Mastitis-Associated Inflammation by Inhibiting CCL-5 Expression in Macrophages. International Journal of Molecular Medicine. 2018 Jan; 41 (1): 340-352. doi: 10.3892/ijmm.2017.3246. Epub 2017 Nov 9. (IF: 2.928, Rank: 65/136)
- Tang H, Peng F, Huang X, Xie X, Chen B, Shen J, Gao F, You J, Xie X, Chen J*. Neoisoliquiritigenin inhibits tumor progression by targeting GRP78-β-catenin signaling in breast cancer. Current Cancer Drug Targets. 2017 Sep 14. doi: 10.2174/1568009617666170914155355. (IF: 2.720, Rank: 136/230, corresponding author).
- 游杰舒,劉煥蘭,陳建萍*。陳建萍從肝論治乳腺癌思路與經驗,新中醫.09-2018;50 (9):250-252,DOI:10.13457/j.cnki.jncm.2018.09.078.
- F Peng, H Tang, C Peng, J Chen*. Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis. Scientific report, 2017. DOI: 10.1038/s41598-017-08422-y. SREP-17-09833. (IF 4.011, Rank: 15/69, Q1, corresponding author)
- F Gao, J Zhang, C Fu, X Xie, F Peng, J You, H Tang, Z Wang, P Li, J Chen * iRGD-modified lipid-polymer hybrid nanoparticles loaded with isoliquiritigenin to enhance anti-breast cancer effect and tumor-targeting ability. International Journal of Nanomedicine. 2017 Jun 1; 12:4147-4162. doi: 10.2147/IJN.S134148. e Collection 2017. (IF: 4.471, Rank: 34/267, Q1, corresponding author)
- X Zheng, J Chen*, Ting Xie, Zhiyu Xia, Wings TY Loo, L Lao, J You, J Yang, K Tsui, F Mo, F Gao. Relationship between dietary patterns of Chinese medicine and the risk of breast cancer in Chinese women in Hong Kong: an epidemiologi-cal survey. Chinese Medicine. 2017, Doi 10.1186/s13020-017-0138-9. (IF: 2.265, Rank: 161/267, Q3, co-first author)
- JQ Chao, JP Chen*, CM Fu, F GAO, XJ Chen. Modern orientation and key problem analysis of the Chinese medicinal tea bag. Journal of Chinese Medicinal Materials No. 40(12), 2017.
- P Liu, J You, WTY Loo, Y Sun, Y He, H Sit, L Jia, M Wong, Z Xia, X Zheng, Z Wang, N Wang, L Lao, J Chen *. The Efficacy of Guolin-Qigong on the Body-mind Health of Chinese Women with Breast Cancer: A Randomized Controlled Trial. Quality of Life Research. 2017 Sep; 26 (9): 2321-2331. (IF: 2.488, )
- N Wang, Y Zheng, J Gu, Y Cai, S Wang, F Zhang, J Chen, H Situ, Y Lin, Z Wang. Network-pharmacology-based Validation of TAMS/CXCL-1 as Key Mediator of XIAOPI Formula Preventing Breast Cancer Development and Metastasis. Scientific report. 2017 Nov; 7 (1): 14513. (IF 4.011,)
- Wang Z, Wang N, Liu X, Wang Q, Xu B, Liu P, Zhu H, Chen J, Situ H, Lin Y.Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages. Int J Mol Med. 2018 Jan;41(1):340-352. doi: 10.3892/ijmm. 2017.3246. Epub 2017 Nov 9.
- F Liang, J Chen*, X Gao, Richard E, Harris, and B Zeng. Current Development and Research in Traditional Chinese Nonpharmacologic Therapy for Pain. Evidence-Based Complementary and Alternative Medicine. 2016; ID 4657572, 1, 2016. doi:10.1155/2016/4657572. (IF:1.984)
- T Yum, T. Zou, Q Ye, H Peng, J Chen*. A Cross-Institution Online Problem Based Learning in Chinese Medicine Education. Asia Pacific Journal of Contemporary Education and Communication Technology 2016; 2(2); (ISSN: 2205-6181).
- T Yum, T. Zou, Q Ye, H Peng, J Chen*. Cross-Institution Collaboration in PBL Education. Asia Pacific Journal of Contemporary Education and Communication Technology 2016; 2(2); (ISSN: 2205-6181).
- J You, J Chen*, J Chan, H Lee, M Wong, W Yeung, L Lao. Effect of YH0618 soup on chemotherapy-induced toxicity in patients with cancer who have completed chemotherapy: study protocol for a randomized controlled. Trials. 2016 Jul 26; 17(1):354. doi: 10.1186/s13063-016-1443-9. (IF: 1.975, Rank: 91/136)
- J Lei, J Chen*, R Ho, J Yu, L Guo, L Li. Music Intervention Can Improve Emotion in Cancer Patients during Disease Progression. Arch Depress Anxiety. 2016; 2(1): 007-009.
- F Peng, C Meng, Q Zhou, J Chen*, L Xiong. Cytotoxic Evaluation against Breast Cancer Cells of Isoliquiritigenin Analogues from Spatholobus suberectus and Their Synthetic Derivatives. Journal of Natural Products. 2016 Jan 22; 79(1):248-51. Doi: 10.1021/acs.jnatprod.5b00774. (IF: 4.257)
- F Wan, F Peng, L Xiong, J Chen*, C Peng, M Dai. In Vitro and In Vivo Antibacterial Activity of Patchouli Alcohol from Pogostemon cablin. Chinese Journal of Integrative Medicine. 2016 Apr 13. [Epub ahead of print]; doi:10.1007/s11655-016-2452-y (IF: 1.445, Rank: 17/27, Q3).
- L Yang, H Tang, Y Kong, X Xie, J Chen, C Song, Liu, F Ye, N Li, N Wang. LGR5 Promotes Breast Cancer Progression and Maintains Stem-Like Cells through Activation of Wnt/β-Catenin Signaling. Stem Cells. 2015 Oct; 33(10):2913-24. doi: 10.1002/stem.2083. (IF:5.614, Rank: 4/26, Q1, co-author)
- X Liu, H Tang, J Chen, C Song, L Yang, P Liu, N Wang, X Xie. MicroRNA-101 inhibits cell progression and increases paclitaxel sensitivity by suppressing MCL-1 expression in human triple-negative breast cancer. Oncotarget. 2015 Aug 21; 6(24):20070-83. doi: 10.18632/oncotarget.4039.(IF:5.008)
- C Song, L Liu, X Pei, X Liu, L Yang, F Ye, X Xie, J Chen, H Tang, X Xie, MiR-200c inhibits breast cancer proliferation by targeting KRAS. Oncotarget. 2015 Oct27; 6(33):34968-78. doi: 10.18632 /Oncotarget. 5198. (IF:5.008)
- F Peng, Q Du, C Peng, N Wang, H Tang, X Xie, J Shen, J Chen*. The Pharmacology of Isoliquiritigenin: A Review: The Pharmacology of ISL. Phytotherapy Research. 2015Jul; 29(7):969-77. doi:10.1002/ptr.5348. (IF: 3.766)
- J Yang, S Yu, Lao, M Yang, J Chen, X Luo, Wang Y, Chen X, Li J, Zhu L, Zheng Q, Hu Y, Wu X, Liang F. Use of moxibustion to treat primary dysmenorrhea at two interventional times: study protocol for a randomized controlled trial. Trials [Internet]. 2015 Jan 30; 16:35. doi: 10.1186/s13063-015-0552-1 (IF: 1.975, )
- W Li, J Liu, R Guan, J Chen, D Yang, Z Zhao, D Wang, Chemical characterization of procyanidins from Spatholobus suberectus and their antioxidative and anticancer activities. Journal of Functional Foods. 2015; 1; 12:468–77. doi: org/1016/j.jff.2014.11.009. (IF: 3.197, Rank: 36/87, Q2, co-author)
- N Wang, Z Wang, Y Wang, X Xie, J Shen, C Peng, J You, F Peng, H Tang, X Guan, J Chen*. Dietary compound isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation. Oncotarget. 2015; 6(12):9854–76. doi:10.18632/oncotarget.3396. (IF: 5.008)
- H Zhu, JD Xu, Q Mao, H Shen, M Kong, JP Chen *, SL Li *. Metabolic Profiles of Dioscin in Rats Revealed by Ultra-performance Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry. Biomedical Chromatography. 2015 Sep; 29 (9): 1415-1421. (IF: 1.748, Rank: 201/267, Q4, corresponding author)
- J Yang, J Chen,L Lao, M Yang, J Chen,L Bo, H Tang, L Yi, H Zheng, X Wu, F Liang. Effectiveness study of moxibustion on pain relief in primary dysmenorrhea: study protocol of a randomized controlled trial. Evidence-based complementary and alternative medicine. 2014; 434978. doi:10.1155/2014/434978. (IF:1.984, Rank: 10/27, Q2, co-author)
- Y Zhang, J Chen, K Zhang, T Wang, M Kong, R Chen, Y Liu, J Chen, Z Wang, J Wang, H Huang. Combination of high ankle-brachial index and hard coronary heart disease Framingham risk score in predicting the risk of ischemic stroke in general population. PLoS One. 2014 Sep 8; 9(9):e106251. doi: 0.1371/journal.pone.0106251. (IF: 2.776)
- Z Wang, N Wang, P Liu, Q Chen, H Situ, T Xie, J Zhang, C Peng, J Chen*. MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin. Oncotarget. 2014; 5(0):1-14. doi:10.18632/oncotarget.2192 (IF: 5.008)
- L Gao, Y Zhou, W Zhong, X Zhao, C Chen, X Chen, Y Gu, J Chen, Z Lv, J Shen. Caveolin-1 is essential for protecting against binge drinking-induced liver damage through inhibiting reactive nitrogen species. Hepatology. May2014; doi:10.1002/hep.27161,60, 687-699, 2014. (IF: 14.971, 5/84, Q1, co-author)
- Y Sun, P Liu, Y Zhao, L Jia, Y He, S Xue, X Zheng, Z Wang, N Wang, J Chen*. Characteristics of TCM constitutions of adult Chinese women in Hong Kong and identification of related influencing factors: A cross-sectional survey. Journal of Translational Medicine. 2014 May 21; 12:140. doi: 10.1186/1479-5876-12-140. (IF: 4.098, Rank: 41/136, Q2, corresponding author)
- Z Wang, N Wang, W Li, P Liu, Q Chen, H Situ, S Zhong, L Guo, Y Lin,J Shen, J Chen*. Caveolin-1 mediates chemo-resistance in breast cancer stem cells via β-catenin/ABCG2 signaling pathway. Carcinogenesis. 2014; 35(10):2346–56. doi:10.1093/carcin/bgu155. (IF: 4.004, Rank: 72/230, corresponding author)
- N Wang, Z Wang, C Peng, J You, J Shen, S Han, J Chen*. Dietary compound isoliquiritigenin targets GRP78 to chemo sensitize breast cancer stem cells via β-catenin/ABCG2 signaling. Carcinogenesis. 2014;35(11):2544–54. doi:10.1093 carcin/bgu187. (IF: 4.004, Rank: 72/230, corresponding author)
- C Cheng, Z Wang, J Chen*. Targeting FASN in Breast Cancer and the Discovery of Promising Inhibitors from Natural Products Derived from Traditional Chinese Medicine. Evidence Based Complement Alternate Med. 2014 Jan; Article ID 232946, 16, doi:10.1155/2014/232946. (IF:1.984,)
- Y Gu, J Chen, J Shen. Herbal Medicines for Ischemic Stroke: Combating Inflammation as Therapeutic Targets. Journal of Neuroimmune Pharmacology. 2014 Jun;9(3):313-39 doi:10.1007/s11481-014-9525-5. (IF: 3.870; Rank: 56/267, Q1)
- S Hahn, Q Tang, F Zheng, S Zhao, J Wu, J Chen. Repression of Integrin-linked Kinase by Antdiabetes Drugs through Cross-talk of PPARγ- and AMPKα-dependent Signaling: Role of AP-2α and Sp1. Cellular Signalling. 2014 Mar; 26 (3):639-647. doi:10.1016/j.cellsig, (IF: 3.388, Rank: 101/193, Q3,)
- F Peng, F Wan, L Xiong, C Peng, M Dai, J Chen*. In vitro and in vivo antibacterial activity of Pogo-stone. Chinese Medicine Journal (Engl). 2014; 127(23):4001-5. PMID: 25430439. (Corresponding author)
- S Hann, Q Tang, F Zheng, S Zhao, J Chen*, Z Wang. Repression of phosphoinositide-dependent protein kinase 1 expression by ciglitazone via Egr-1 represents a new approach for inhibition of lung cancer cell growth. Molecular Cancer. 2014 Jun 13; 13:149. doi:10.1186/1476-4598-13-149. PMID:24925061. (IF: 10.679, Rank: 17/299, Q1)
- S Hann, J Chen, Z Wang F Zheng, S Zhao. Targeting EP4 by Curcumin through cross Talks of AMP-dependent Kinase Alpha and p38 Mitogen-activated Protein Kinase Signaling: The Role of PGC-1α and Sp1. Cellular Signalling. 2013 Aug; 25 (12): 2566-2574. doi:10.1016/j. cellsig. 2013.08.020. (IF: 3.388, Rank: 101/193, Q3,)
- Z Wang, N Wang, S Han, D Wang, S Mo, L Yu, H Huang, K Tsui, J Shen, J Chen*. Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Neoangiogenesis via VEGF/VEGFR-2 Signaling Pathway. PLoS One. 2013 Jul; 5, 8 (7): e68566. doi: 10.1371/journal.pone.0068566. (IF: 2.776, Rank: 24/69, Q2,)
- H Peng, K Zhang, L Xiao, Z Yuan, J Chen, Z Wang, J Wang, H Huang. The Insufficiency Intake of Dietary Micronutrients Associated with Malnutrition-inflammation Score in Hemodialysis Population. PLoS One. 2013 Jun; 8 (6): e66841. doi:10.1371/journal. pone.0066841. (IF: 2.776, Rank: 24/69, Q2, co-author)
- Z Wang, D Wang, S Han, N Wang, F Mo, T Loo, J Shen, H Huang, J Chen*. Bioactivity-guided Identification and Cell Signaling Technology to Delineate the Lactate Dehydrogenase an Inhibition Effects of Spatholobus Suberectus on Breast Cancer. PLoS One. 2013 Feb; 8(2): e56631. doi:10.1371/journal.pone.0056631. (IF: 2.776, Rank: 24/69, Q2,)
- J Li, X Wu, Y Chen, Z Tang, Y Xu, J Jiang, Y Gu, J Chen, D Yang, D Wang. Antidiarrheal Properties of Different Extracts of Chinese Herbal Medicine Formula Bao-Xie-Ning. Journal of Integrative Medicine. 2013 Mar; 11 (2): 125-134.doi:10.3736/jintegrmed2013019 (IF: 1.445, Rank: 17/27, Q3)
- P Liu, Y Sun, Y He, Z Wang, N Wang, L Jia, X Zheng, W Loo, L Chow, J Chen*. Identification of risk factors for emotional disorders among Chinese women following breast cancer surgery. European Journal of Cancer. 2013 Mar; 49 (1): S21. doi:10.1016/S0959-8049(13)70053-4 (IF: 6.680, Rank: 26/230, Q1)
- N Wang, Z Wang, L Chow, W Loo, J Shen, J Chen*. Dietary Compound Isoliquiritigenin Increases Breast Cancer Chemosensitivity by Limiting Cancer Stem Cells via Beta-catenin Signaling. European Journal of Cancer. 2013 Mar; 49 (1): S20-S21. doi:10.1016/S0959-8049(13)70052-2. (IF: 6.680, Rank: 26/230, Q1, corresponding author)
- J Liang, J Chen, Z Tan, J Peng, X Zheng, K Nishiura, J Ng, Z Wang, D Wang, Z Chen, L Liu. Extracts of the medicinal herb Sanguisorba officinalis inhibit the entry of human immunodeficiency virus-1. Journal of Food and Drug Analysis. 12/2013; 21(4):S52-S58. Doi: 10.1016/j.jfda.2013.09.034. (IF: 4.176, Rank: 49/267, Q1, co-author)
- Y He, X Zheng, Cindy Sit, Wing T Loo, Z Wang, T Xie, B Jia, Q Ye, K Tsui, Louis W Chow, J Chen*. Using association rules mining to explore pattern of Chinese medicinal formulae (prescription) in treating and preventing breast cancer recurrence and metastasis. Journal of Translational Medicine. 2012 Sep 19; 10 Suppl 1:S12. doi:10.1186/1479-5876-10-S1-S12. (IF: 4.098, Rank: 41/136, Q2, corresponding author)
- W He, D Wang, Z Ye, W Qian, Y Tao, X Shi, L Liu, J Chen, L Qiu, P Wan ,X Jia, X Li, C Gao. Application of a Nanotechnology Antimicrobial Spray to Prevent Lower Urinary Tract Infection: A Multicenter Urology Trial. Journal of Translational Medicine. 2012 Sep 19; 10 Suppl1:S14. doi:10.1186/1479- 5876-10-S1-S14. (IF: 4.098, Rank: 41/136, Q2,)
- Z Wang, Y Cheng, N Wang, D Wang, Y Li, F Han, J Shen, D Yang, X Guan, J Chen*. Dioscin Induces Cancer Cell Apoptosis Through Elevated Oxidative Stress Mediated by Downregulation of Peroxiredoxins. Cancer Biology & Therapy. 2012 Feb; 13 (3): 138 - 147. doi: 10.4161/cbt.13.3. 18693. Epub2012Feb1 (IF: 2.879, Rank: 124/230).
- Z Wang, T Loo, N Wang, Louis W Chow, D Wang, F Han, X Zheng, J Chen*. Effect of Sanguisorba officinalis L on breast cancer growth and angiogenesis. Expert Opinion on Therapeutic Targets. 2012 Mar; 16 Suppl 1:S79-89. doi:10.1517/14728222.2011.642371. (IF: 4.621, Rank: 31/267, Q1, corresponding author)
- N Wang, Z Wang, S Mo, T Loo, D Wang, H Luo, D Yang, Y Chen, J Shen, J Chen*. Ellagic Acid, a Phenolic Compound, Exerts Anti-angiogenesis Effects via VEGFR-2 Signaling Pathway in Breast Cancer. Breast Cancer Research and Treatment. 2012 Aug; 134 (3): 943-955.doi:10.1007/S10549-012-1977-9. (IF: 3.471, Rank: 90/230, Q2, corresponding author)
- Z Wang, T Loo, J Shen, N Wang, D Wang, D Yang, S Mo, X Guan, J Chen*. LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis. Breast Cancer Research and Treatment. 2012; 131(3):791–800.doi:10.1007/S10549-011-1466-6Epub2011Mar31 (IF: 3.471, Rank: 90/230, )
- Z Wang, N Wang, J Chen*, J Shen. Emerging Glycolysis Targeting and Drug Discovery from Chinese Medicine in Cancer Therapy. Evidence Based Complementary and Alternative Medicine. 2012; 873175. doi:10.1155/2012/873175. (IF:1.984, Rank: 10/27, Q2, corresponding author)
- Z Li, D Yang, M Huang, X Hu, J Shen, Z Zhao, J Chen, D Yang. Chrysomya Megacephala (Fabricius) Larvae: A New Biodiesel Resource. Applied Energy. 2012 Mar; 94: 349-354. doi.org/10.1016/j (IF 4.781/ 4.783).
- X Yang, B Huang, J Chen, S Huang, H Zheng, Z Lun, J Shen, Y Wang, L Lu. In vitro effects of aqueous extracts of Astragalus membranaceus and Scutellaria baicalensis GEORGI on Toxoplasma gondii. Parasitology Research. (2012) 110:2221–2227.doi: 10.1007/s00436-011-2752-2. (IF: 2.027).
- D Leung, D Yang, Z Li, Z Zhao, J Chen, L Zhu. Biodiesel from Zophobas Morio Larva Oil: Process Optimization and FAME Characterization. Industrial & Engineering Chemistry Research. 2012 Jan; 51: 1036–1040.doi:10.1021/ie201403r. (IF: 2.567)
- X Yang, B Huang, J Chen, S Huang, H Zheng, Z Lun, J Shen, Y Wang, F Lu. In Vitro Effects of Aqueous Extracts of Astragalus Membranaceus and Scutellaria Baicalensis GEORGI on Toxoplasma Gondii. Parasitology Research. 2012 Jun; 110 (6):2221-2227. doi:10.1007/s00436-011-2752 -2.Epub 2011Dec17 (IF : 2.027)
- Z Wang, T Loo, J Shen, N Wang, D Wang, D Yang, S Mo, X Guan, J Chen*. LDH-A Silencing Suppresses Breast Cancer Tumorigenicity Through Induction of Oxidative Stress Mediated Mitochondrial Pathway Apoptosis. Breast Cancer Research and Treatment. 2012 Feb; 131 (3): 791-800.doi:10.1007/s10549-011-1466-6 (IF: 4.085).
- W Lee, M Xu, Y Li, Y Gu, J Chen, D Wong, P Fung, J Shen. Free cholesterol accumulation impairs antioxidant activities and aggravates apoptotic cell death in menadione-induced oxidative injury. Archives of Biochemistry and Biophysics.2011 Oct; 514(1-2):57-67.doi:10.1016-j.abb.2011.07.014.
- H Liu, J Liu, M Yang, J Chen, D Wang. Comparison of Two Determination Methods for Astragaloside Ⅳ in Radix Astragali. Traditional Chinese Drug Research and Clinical Pharmacology. 2011; 22(6): 659-662.
- J Liu, Z Liu, D Wang, M Li, S Wang, J Chen, Y Wang, D Yang. Induction of Apoptosis in K562 Cells by Dicyclohexylammonium Salt of Hyperforin through a Mitochondrial-related Pathway. Chemico Biological Interaction. 2011 Apr; 190 (2-3): 91-101.10.1016/j.cbi.2011.02.026. Epub2011Mar3. (IF: 2.618)
- W Lee, M Xu, Y Li, Y Gu, J Chen, D Wong, P Fung, J Shen. Free Cholesterol Accumulation Impairs Antioxidant Activities and Aggravates Apoptotic Cell Death in Menadione-induced Oxidative Injury. Archives of Biochemistry Biophysics. 2011 Oct; 514 (1-2): 57-67. doi:10.1016/j, abb.2011.07.014. (IF 2.807)
- J Shen, W Lee, J Chen, D Yang. Caveolin-3 Peptide Protects Cardiomyocytes from Apoptotic Cell Death via Preserving Superoxide Dismutase Activity and Inhibiting Caspase-3 Activation under Hypoxia-reoxygenation. Am J Biomed Sci. 2011 Mar; 3 (2): 126-144. Doi: org/10.5099/aj110200126. (IF 1.334)
- J Chen*, S Chiu, H Chok. Prevention Strategies for Recurrence and Metastasis of Breast Cancer by Chinese Medicine. Global Traditional Chinese Medicine.2011; 4 (2):125.
- Y Cheng, Z Wang, D Wang, H Liu, H Liu, J Chen*.Total Flavonoids and its Anti-tumor Activities by Different Solvent Extract from Spatholobus suberectus Dunn. Chinese Journal of Experimental Traditional Medical Formulae 2011,17(9): 187.
- F Zeng, Y Cheng, J Chen, Z Wang, M Wan. Study on in vitro antiviruses of different extracts from Caulis Spatholobus. Traditional Chinese Medicine new Drug and clinical pharmacology. 2011, 22(1): 16-20.
- Y Cheng, Y Fu, Z Wang, D Yang, J Chen*, D Wang. Determination on the contents of Condensed Tannins in Spatholobus suberectus Dunn and Primary study on their anti-cancer actives. Scientiarum Naturalium Universitatis Sun Yatseni. 2011;50 (2):75-80.
- Y Fu, Y Cheng, J Chen*, M Wang. Advances in studies on chemical substances, pharmacology and quality evaluation of Caulis Spatholobi. Chinese Traditional and Herbal Drugs 2011; 42(6):1229.
- 58) Y Cheng, J Chen, J Chen*, D Wang. Determination on the contents of different type of tannins in Sanguisorba officinalis L. extracts. Chinese Traditional Patent Medicine, 2011; 33(5):852-57.
- Z Wang, D Wang, T Loo, Y Cheng, L Chen, J Shen, D Yang, L Chow, X Guan, J Chen *. Spatholobus suberectus inhibits cancer cell growth by inducing apoptosis and arresting cell cycle at G2/M checkpoint. Journal of Ethno Pharmacology. 2011 Jan 27; 133(2):751-8. doi:10.1016/j.jep.2010.11.004. (IF: 3.055)
- X Lin, S Sze, Y Tong, Z Zhang, Y Feng, J Chen, T Ng, X Lin, et al., Protective Effect of Dendrobium Officinale Polysaccharides on Experimental Sjögren’s Syndrome. Journal of Complementary and Integrative Medicine. 2010 Apr;7 (1): 1-18.
- X Yang, S Huang, J Chen, N Song, L Wang, Z Zhang et al. Evaluation of the adjuvant properties of Astragalus membranaceus and Scutellaria baicalensis GEORGI in the immune protection induced by UV-attenuated Toxoplasma gondii in mouse models. Vaccine. 2010 Jan 8; 28(3):737-743. doi:10.1016/j.vaccine. (IF3.412).
- Zhai, Z Liu, J Li, J Chen, L Jiang, D Wang, J Yuan, J Shen, D Yang, J Chen. Different mechanisms of cis-9, trans-11- and trans-10, cis-12- conjugated linoleic acid affecting lipid metabolism in 3T3-L1 cells. The Journal of Nutritional Biochemistry. 2010 Nov; 21(11):1099-105. doi: 10.1016/j.jnutbio.2009.09.007. (IF: 4.668).
- T Loo, J Jin, N Cheung, Y Douand, J Chen*. Polistes olivaceous decreases biotic surface colonization. African Journal of Biotechnology. 2009; 8 (24): 7094-7100.
- Q Li, L Jiang; D Yang, J Chen; D Wang. Extraction of Total Alkaloids from Corydalis saxicola Bunting by the Macroporous Resin. Chinese Journal of Pharmaceuticals.2009;40(10)750-54.
- J Lu, D Wang, a Miao, D Yang, J Chen. HPLC-DAD-MS/MS analysis of purine alkaloids and tea polyphenols in young leaves of Yinghong 1 Yinghong 9 and Qimen cultivars. Journal Scientiarum Naturalium, Universitatis Sun Yatseni 2009; 48 (1): 72-75.
- Q Li, Q Chao, L Jiang, D Yang, J Chen, D Wang. Extraction of Total Alkaloids from Corydalis saxicola Bunting by Enzymatic Method. Research and Practice on Chinese Medicines. 2009; 23 (4): 47.
- W Mao, T Wang, H Zeng, Z Wang, J Chen, J Shen, Synthesis and evaluation of novel substituted 5-hydroxycoumarin and pyranocoumarin derivatives exhibiting significant antiproliferative activity against breast cancer cell lines. Bioorganic & Medicinal Chemistry Letters. 2009; 19 (16):4570–4573(IF: 2.486).
- H Ren, M Jin, X Li, B Tan, D Wang, Wings T Loo, Barry H Yeung, D Yang, J Chen*. The disposition and pharmacokinetics of extract from Dioscorea nipponica Makino in rats. African Journal of Biotechnology. 2008; 7(22): 4015-18.
- H Liang, Wings T Loo, Barry H Yeung, Mary N Cheung, M Wang, J Chen*. A non-toxic herbal remedy, which enhances lymphocyte activity and cytokine secretion. African Journal of Biotechnology. 2008; 7 (22):4010-14.
- C Diu, Y Luo, J Chen*. Review Radix rule application of heat in clinic. Medicine Journal of Guangzhou University of Traditional Chinese. 2008; 3(25):259-61.
- L Sui, J Li, D Wang, L Zhu, J Chen, D Yang. Quik Prep HSCCC application system of conjugated linoleic acid isomers and their separation. Laboratory analysis. 2008; 27:253-59.
- S Wang, X Yang, S Jiang, J Chen, S Houng, F Lu. Toxoplasma infection intrauterine vertical transmission characteristics of the immune. Journal of Tropical Medicine. 2008; 8(5):505-07.
- Y Zeng, R Deng, Barry, H Yeung, Wings Y. Loo, Mary B. Cheung, J Chen, Bingrong Zhou, Y Fu, L Huang, M Lu, M Wang. Application of an antibacterial dressing spray in the prevention of post-operative infection in oral cancer patients: A phase 1 clinical trial. African Journal of Biotechnology. 2008; 7 (21): 3827-31.
- S Lin, D Wang, D Yang, J Yao, Y Tong, J Chen*. Characterization of steroidal saponins in crude extract from Dioscorea Nipponica Makino by liquid chromatography tandem multi-stage mass spectrometry. Analytica Chimica Acta. 2007; 599: (9); 98-106. doi: 10.1016/j.aca. (IF: 4.712).
- T Wang, J Chen*, H Huang, J Shen, D Yang, D Wang. Protective effects of Diosgenin against myocardial in jury induced by ischemia and reperfusion in rat. Critical Care Medicine. 2007; 37(12): 840(IF: 7.422).
- W Loo, J Chen *, L Chow, J Chou. Effects of Shugansanjie Tang on Matrix Metalloproteinases 1, 3 and 9 and Telomerase Reverse Transcriptase Expression in Human Breast Cells in Vitro. Biomed Pharmacother. 2007 Oct; 61 (9): 601-605.doi:10.1016/j.biopha. (IF:2.326)
- Y Law, S Mo, J Chen*. The functions and applications of “Adjuvant drug”from Fresh Ginger,Chinese Date and Liquorice Root in Zhongjing’s Prescription. Chinese Journal of Experimental Traditional Medical Formulae. 2006; 33(3):22-24.
- X Li, M Jin, J Chen*. Adjuvant drug” from Fresh Ginger、Chinese Date and Liquorice Root in Zhongjing’s Prescription. Journal of Guangdong College of Pharmacy. 2006; 22(3): 243-46.
- J Chen*, F Han, C Han, K Li, B Yang. Effect of Yigan Granules on Bile Secretion in Rats. Traditional Chinese Drug Research & Clinical Pharmacology.2005; 16(6):412-14.
- S Mo, Y Law, J Chen*. The modification rules of Ephedra and Liquorice Root in Treatise on Febrile and Miscellaneous Disease. New Journal of Traditional Chinese Medicine .2005; 37(12):9-10.
- F Han, J Chen*, T XIE, K Zhao, C Han. The Effect of Yi-gan Granules on the Immunity Function of Mice. Lishizhen Medicine and Materia Medica Research. 2004; 52(4):33-7.
- H Ren, J Chen, Q Long, Reviewed research of Diaoxinxiekang Chinese herbs. Pharmacy of China.2003; 22(6):373-4.
- Y Zhang, Y Huang, J Chen, Z Deng, J Xiao. Protective Effect of Ganmeiling Injection on Chronic Hepatic Injury in Rats. Chinese herbs. 2003; (2):22.
- J Chen*, D Chen. Xeimeitong herbs protect anoxic damnification of experiment. Chinese Journal of Experimental Traditional Medical Formulae .2002; 21(2):18.
- Y Zhang, Y Huang, J Chen*, Ganmeiling for effect on immunity of rat. Hospital Pharmacology of China. 2002; 33(9):33.
- B Tan, G Wu, J Chen, W Wu, L Li, L Tang, Analysis of Sini decoction used HPLC. Chinese herbs (J) 2001; 19(1):20.
- J Chen*, D Chen, Xeimeitong herbs effect on remembers of rat. New drug and Hospital Pharmacology .2001; 22(4):32.
- Y Huang, Y Zhang, J Chen*, Ganmeilin protact for liver damnification. Hospital Pharmacology of China .2001; 23(7):32.
- Y Huang, J Chen, Y Zhang Analysis of Ganmeiling component used HPLC. Hospital pharmacology of China. 2001; 22(6):30.
- J Chen*, B Tan, W Wu, L Li .Sini decoction prescription rate on two herbs. Chinese Journal of Experimental Traditional Medical Formulae. 2001; 33(3):22.
- Q Zhang, D Maddock, S Heo, C Chiu,D Lai , K Souza, S Mehta, Y Wan, J Chen, et al. Cytokine-induced P38 activation feedback regulates the prolonged activation of akt cell survival pathway initiated by reactive oxygen species in response to UV irradiation in human Kerationocytes. International Journal of Oncology. 2001 Nov; 19(5):1057-61. doi:10665009 (IF: 3.018).
- J Chen*, W Wu, M Zhang, T Tang, F Han. The Ideas and Ways on the Research of the Rule of the Compatibility of Medicines in a Prescription. Chinese Journal of Experimental Traditional Medical Formulae. 2000; 1:1.
- H Huang, J Chen., The mechanism of the cardiac myocyte apoptosis of mouse with Pituitary. International Journal of Cardiology .2000; 21, 54.
- Y Huang, J Chen, Y Zheng. Quality control of Ganhuang injection. Chinese herbs 2000;31(1):20.
- H Huang, J Chen*, Molecular Level (CGRP) Research Sini Decoction Effect on Myocardial Ischemia. Journal of Cardiovascular Research. 2000; 10:5.
- X Qian, Y Chen, J Chen, and W Wu. Fufang Xueshuantong capsule X on the protective effect of ischemic myocardium. The Journal of Practical Medicine. 2000;11:(16):900.
- H Yang, W Wu, J Chen, L Zhou, C Cheng. Effect of Baoxin capsule on homodynamics of myocardial ischemia in canine. Chinese Journal of Pathophysiology. 2000; 16(3): 218.
- H Huang, J Chen*. The mechanism of the cardiac myocyte apoptosis. Tibetan Journal of Medicine 2000;21(2):30
- H Tan, J Chen, W Wu et al. Protective effect of compound Xueshuantong capsule on experimental ischemic myocardium of canine. Journal of First Military Medical University. 2000; 20(3):241.
- H Yang, J Chen, W Wu et al. Effect of Baoxin capsule on protecting of myocardial ischemia. Chinese Journal of Integrated Traditional and Western Medicine. 2000; S1 July.
- J Chen*, F Han. The Curative Effect of Yigan Drug on Experimental Acute Hepatic Injury in Mice. Journal of the First Military Medical University. 2000; 21: 123.
- J Chen* et al. Sini decoction effect on cell of cardiac myocyte. International Journal of Cardiology. 1999; 1: 23. (IF:4.638)
- J Chen*, F Han, C Han. The Effect of Yigan drug granules on bile rate of flow in rat. Tibetan Journal of Medicine .1999; 53, 33.
- J Chen*, W Wu, H Tan, Sini Decoction Effect on Coronary Blood Flow of Myocardial Ischemia. Journal of the First Military Medical University .1999; 19:120.
- H Huang, J Chen, W Wu. A new mode of ischemia/reperfusion to induced the cardiac myocyte apoptosis. Chinese Journal of Cardiovascular Medicine. 1999; 4(3):159.
- H Luo, H Huang, X Liu, J Chen. Experimental research on the protective effect of Sini decoction on acute ischemic myocardium. Chines Journal of Pathophysiology .1999; 15(11):994.
- X Qian, W Wu, J Chen, and H Tan. Effects of Fufang Xueshuantong capsule on hemodynamics in myocardial ischemic canines. Chinese heart journal. 1999; 11 :( 3):159.
- H Luo, J Chen, H Tan. Effects of HuangQi injection on hypoxia in mice. Shenzhen Journal of Integrated Traditional and Western Medicine .1999; 9(3):21.
- L. Zhou W Wu, J Chen. Effects of Fufang Xueshuantong capsule on ECG in myocardial ischemic model of canines. Shenzhen Journal of Integrated Traditional and Western Medicine. 1999; 9(2):18.
- T Tang, J Chen, W Wu, H Huang. The Effect of Sini Decoction on Hemorheology of blood stasis model of rat. Chinese Journal of Hemorheology. 1999; 9(3):139.
- J Chen*,W Lu. Containing drugs (Ge Huang Tang) serum endogenous impact caused by heat factor. Tibetan Journal of Medicine .1999;19(3):44.
- HQ Huang, J Chen. Differential diagnosis about wide QRS wave tachycardia. China Medical Abstracts.1999; 16 (supplement).
- J Chen* H Huang. Relationship between CGRP to heart disease. Journal of Medicine for Altiplano 1998; 26(3):17.
- J Chen*, Z Lua, M Zhang, Z Zhang. G Huang Decoction Effect on IL-6. Academic Journal of Sun Yat-sen University of Medical Sciences .1998; 18:75.
- J Chen*, Z Zhang. Progress of Weifen Syndrome of Febrile Diseases. China Journal of Basic Medicine in Traditional Chinese Medicine .1998; 4: 58.
- J Chen* Z Zhang, Rheum Palmatum L. Used in Weifen Syndrome of Febrile Diseases. Journal of Guangzhou university of TCM. 1998; 15: 5.
- J Chen* Z Zhang. The Influence of Gehuang Decoction Serum on Endogenous Pyrogen. Journal of Chinese Traditional and Herbal Drugs.1998; 29: 96.
- J Chen* Z Zhang. Z Lua, A further understanding of the Method of Relieving Exterior Syndrome with Pungent and Cool Drugs. China Journal of Basic Medicine in Traditional Chinese Medicine .1998; 4: 34.
- J Chen*.H Huang, F Han. The Influence of Gehuang Decoction Serum in Killing Streptococcus. Tibetan Journal of Medicine .1998; 52: 43.
- J Chen*, Z Zhang, Z Lua. Prevent Wei stage from qi in Febrile Diseases before take bitter and cold herbs. Journal of Traditional Chinese Medicine. 1998; 39, 443.
- T Liang, J Chen, H Tan. The effect of Co-xueshuantong capsule on hypoxia in mice. Shenzhen Journal of Integrated Traditional and Western Medicine.1998; 98(4):16.
- E Yuan, Z Liu. J Chen. Effects of Di-ao-xin-xue-kang on hemodynamics in renovascular hypertensive rats. Journal New Drugs and Clinical Remedies. 1994; 13(3):147-9.
- E Yuan, Z Liu. J Chen. Effect of DAXXK On experimental myocardial injury and relational with DAXXK modulate platelet function and metabolism. Journal Clinical Cardiology.1994; 10(6):357-8.
- G Zhang, S Yan, J Jiang, J Chen, R Zhou, H Zeng. Study on Relation between Epigastralgia and Electrogastrogram or Pylori Helicobacter. Chinese Journal of Integrated Traditional and Western Medicine on Gastro-spleen.1994;2(4):38.
- H Chen, S Mo, Y Zhou, Z Zhou, J Chen. Influence of Di-ao-xin-xue-kang on ~ (45) Ca transmembrane influx in rat aorta. Journal New Drugs and Clinical Remedies. 1994; 13(3):133-9.
- R Yuan, Z Liu, J Chen. Protective effect of Di-ao-xin-xue-kang on myocardial damage induced by isoprenaline in rats. Journal New Drugs and Clinical Remedies .1994; 13(3):120-5.
- J Chen*. Jieduhuayu of Strategy treatment is used in fever disease use. Journal of Chengdu University of Traditional Chinese Medicine. 1992; 15 (2): 1.
- D Huang, J Chen, Y Yu. Diaoxinxuekang capsule be used on palpitations. Journal of Chengdu University of Traditional Chinese Medicine .1990; 13(4):26.
- L Kui, Z Zhang, J Chen*. Analysis the status of fever disease on research and clinic. Journal of Chengdu University of Traditional Chinese Medicine. 1989; 12 (2): 7.
- L Luo, W Xu, J Chen*. The experience of Governance atrophy soup for muscular dystrophy. Chinese Journal of Integrated Traditional and Western Medicine. 1987; 25(4):202.
2021
2020
2019
2018
2017
2016
2015
2014
2013
2012
2011
2010
* As correspondence or first author.
C. Conference Papers
- TCM music causes remission of promoted breast cancer growth by managing depression-like behaviors in mice and in clinic. Global Experts Meeting on Frontiers in Traditional & Alternative Medicine. Presented in London 2019.
- Metabolomics study of ethanol extract from Caulis Spatholobi(EECS)on weight loss via energy metabolism. Presented in Belin 2019.
- Angelica sinensis induces estrogen receptor-positive breast cancer growth via estrogen receptor mediated activation in vitro and in vivo. Presented in Italy 2018L Jia, J Chen *. Exploration and characterization of the Role of Chronic Mild Stress in Promoting Breast Cancer in Transgenic Mice. Guangzhou No1 integrated traditional and Western medicine in Breast disease 2016-3-26.
- J Chen *, Y Sun. Relationship between Constitution of TCM and Breast cancer in Guangzhou No1 integrated traditional and Western medicine in Breast disease 2016-3-26.
- J Chen *. Incidence of breast cancer with micro- environment of TCM (visiting speaker) in Guangzhou NO 1 integrated traditional and Western medicine in Breast disease 2016-3-26.
- T Yum, T.X Zou , Q Yec , H Peng , J Chen *. The Second Asia Pacific Conference on Advanced Research (A CROSS-INSTITUION ONLINE PROBLEM BASED LEARNING IN CHINESE MEDICNE EDUCATION.PCAR-2016.2) in Melbourne, Australia (visiting speaker).
- T Yum, T.X Zou , Q Yec , H Peng, J Chen *. Cross-Institution Collaboration in PBL Education The Second Asia Pacific Conference on Advanced Research (APCAR-2016. 2) in Melbourne, Australia (visiting speaker).
- J Chen *. Chapter editor, TCM Culture book in Shenzhen 2016-1-11-12.
- J Chen*. Effects of 5-element music on female patients of breast cancer with mental disorders after surgery” 9th PDY international symposium On TCM. Dec 04 2015.
- J Chen*. TCM Culture textbook “TCM theory about emotion on Breast cancer” Guangzhou University of TCM Nov06- 07.
- J Chen*. 2015sumposium on international consortium for Chinese Medicine and cancer Dalian Oct 16-18.
- J Chen*. An Epidemiological Study of the Relationship between Dietary Patterns of TCM and the Risk of Breast Cancer in Hong Kong Chinese Women CGCM 2015 in Canada.
- F Peng, J Chen*.The Inhibitory Effect of Isoliquiritigenin/Spatholobus Suberectus on Breast Cancer Metastasis---- a Process Modulated by the Up-expression of miR-374a and Down-expression of miR-200c CGCM, (08 / 2015) in Canada.
- J You, J Chen *,the efficacy of Guolin-Qigong on the body-mind health of hinese women with Breast Cancer: a randomized controlled trial. CGCM, (08 / 2015) in Canada.
- L Jai, J Chen*. Exploration and characterization of the Role of Chronic Mild Stress in Promoting Breast Cancer in Transgenic Mice. Nov29 2014, international health conference in Guangzhou.
- J Chen*. THE INTERNATIONAL PROCESSES OF TCM SPORTS & HEALTH. Nov29 2014, international health conference in Guangzhou.
- J Chen*. Chinese medicine SS (23th Nov 2014. In Macau culture of Chinese Medicine).
- J Chen*. When Chinese Medicine meet Breast cancer the 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine, The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research(15-16th, Nov2014, HKU).
- J Chen*. Chinese medicine idea of depress on Breast cancer. Liyi excerpted of Breast cancer.Nov.2014in Guiling.
- J Chen*. Constitution of Chinese medicine 1-2 Nov 2014-Houston.
- J You, J Chen*.Qigong promotion recover of breast cancer Co-chairman of the Clinical Investigation I (Cancer, Liver Disease and Inflammation) and speaker. CGCM2014 Beijing.
- J Chen*. ISL in breast cancer OOTR Translational Oncology Session at Israel on June 19, 2014.
- Z Wang, N Wang, J Shen and J Chen* LDH-A, a potential molecular target for cancer therapy and development of specific Inhibitors from Spatholobus suberectus. 19th Hong Kong international Cancer Congress (8-9th Nov 2012 HK).
- T.Y Loo, M.N Cheung, L.W Chow, M Wang and J Chen*. Evaluation of the Psychological and Biological Changes of Patients Diagnosed with Benign and Malignant Breast Tumor. 19th Hong Kong international Cancer Congress (8-9th Nov 2012 HK).
- T.Y Loo, M.N Cheung, L.W Chow, M Wang and J Chen*. Similarity of Hypermethylation of TIMP-3, GSTP-1 and 14-3-3 Sigma Genes and Irreversible Changes in Chronic Periodontitis and Cancer Patients.19th Hong Kong international Cancer Congress ( -9th Nov 2012 HK).
- J Chen*, T.Y Loo, Z Wang. Using association rules mining to explore compatibility of Chinese medicinal formulae (prescription) which treat and prevent breast cancer recurrence and metastasis. (Speaker). 12th national Traditional Chinese Medicine integrative Medicine of Breast disease In Beijing 2011(28-30th Oct).
- J Chen*, T.Y Loo, Z Wang. Cancer with emotion. 18th Hong Kong international Cancer Congress (3-5th Nov 2011 HK).
- J Chen*, N Wang, T.Y Loo, Z Wang. J. Ellagic Shen. Acid exerts anti-angiogenesis effect on VEGF-induced endothelial cells via VEGFR-2 signaling pathway in breast cancer. 17th international Biophysics Congress Beijing 2011(30th Oct- 3ed Nov).
- J Chen*. Study on Association Rule Ming in Chinese Medicine research for the breast cancer metastasis. 2th international Cancer Congress in Guangzhou (16-18th Nov 2011 GZ).
- J Chen*, T.Y Loo, Z Wang. Dietary pattern relationship with Breast cancer, 2011 OOTR, Hong Kong.
- J Chen*, T.Y Loo, Z Wang. Relationship between liver blood deficiency and female breast cancer in the view of the TCM, 49th World Congress of Integrated Medicine held in KuaIa Lumpur, Malaysia( Speaker) , 2011.
- J Chen *, T.Y Loo, Z Wang. A case-control study of the relationship between Dietary Patterns of TCM and the Risk of Breast Cancer in, OOTR, 2011 Hong Kong.
- N Wang, Z Wang, T.Y Loo, J Chen *Ellagic Acid, a phenolic compound, exerts anti-angiogenesis effect through VEGF production and VEGFR-2 signaling pathway, OOTR, 2011.
- J Chen*, T.Y.J Li, T.Y Loo, Z Wang. CORRELATIONAL STUDY ON THE FIVE PERSONALITIES AND BREAST CANCER, OOTR, 2011.
- Z Wang, T.Y Loo, N Wang, Y Chow, J Chen*. Inhibition of Breast Cancer Growth and Angiogenesis by a Medicinal Herb: Sanguisorba officinalis L, 2011.
- J Chen *. Relationship between liver blood deficiency and female breast cancer in the view of the TCM, the 49th World Congress of Integrated Medicine held in KuaIa Lumpur, Malaysia, 2011.
- Z Wang, T.Y Loo, N Wang, J Chen*. Proteomic Identification of Anti-cancer Proteins in Dioscin-treated Human Esophogeal Cancer Kyse510 cells, OOTR, 2011.
- J Chen*, S Chiu, Z Wang, T.Y Loo. Prevention Strategies for Recurrence and Metastasis of Breast Cancer by Chinese Medicine, OOTR, 2011.
- Z Wang, T.Y Loo, D Wang, Y Cheng, X.Y Guan, J Chen*. Spatholobus suberectus, a potential Chinese herb for cancer treatment, OOTR the 6th Annual Conference, 2010.
- J Chen*. Chinese Medicine anticancer from SS. Oxidative stress in Taiwan, 2010.
- T.Y Loo, Z Wang, C.K Diu, W Yeung, J Chen *. Predominance of left-sided breast cancer: an explanation from a traditional Chinese medicine approach and its treatment implication, The 8th European Congress on Menopause in UK, 2009.
- Z Wang, T.Y Loo, J Chen*. Safety of Chinese Medicine ---use of Dongguan to treat female disease: is it appropriate? The 5th Meeting of Asian Breast Cancer Society, Macau, 2009.
- J Chen*, T.Y Loo, Z Wang. Soft-ware for history of patients. (Speaker). 11th national Traditional Chinese Medicine, integrative Medicine of Breast disease In Guilin 2009(16-18 th Oct).
- Z Wang, X.Y Guan, J Chen*. Anti-tumor effects and mechanisms of Spatholobus suberectus water extracts in vitro and in vivo. 2009, 98. GCCM.
- Y Li, J Chen*, T.Y Loo. Immunomodulatory effect of Yupingfeng (YPF) on human lymphocytes in vitro, Organization for Oncology and Translational Research (OOTR) 4th Annual Conference, Hong Kong, 2007.
- J Chen*. Prevention and treatment of breast cancer by Chinese Medicine 2007 TWGHs Eddie Wang symposium on integrated Chinese and western Medicine, Hong Kong, 2007.
- J Chen*. Breast cancer treatment strategy in Chinese Medicine (speaker), WDY's conference, Hong Kong, 2007.
- J Chen*.Treatment strategy of Chinese Medicine on breast cancer, WDY's academically conference, Hong Kong, 2007.
- J Chen*, T.Y Loo. Immunomulatory effect of YPF on human lymphocytes in vitro. The 6th biennial meeting of the Asian Breast Cancer Society, Hong Kong, 2007.
- J Chen*, T.Y Loo, W.K Chou. Juzen-taiho to enhances immune activity in vitro and minimizes cyto-toxicity in vivo, The 6th Biennial meeting of Asian Breast Cancer Society, Hong Kong, 2007, p 31.
- T.Y Loo, J Chen*, W.C Chow. A non-toxic herbal remedy which enhance lymphocyte activity and cytokine secretion: Takayama Ganoderma Lucidum, The 6th Biennial meeting of Asian Breast cancer society, Hong Kong, 2007, p 109.
- Y Li, T.Y Loo, X.Y Guan, J Chen*. Anticancer effect if Dioscin in breast and esophageal cancer cells, The 6th Biennial meeting of Asian Breast Cancer Society, Hong Kong, 2007.
- T.Y Loo, J Chen*, W.C Chow. Traditional Chinese medicine, Rhodia, prevents oral membrane ulceration in patients undergoing chemotherapy: a novel discovery, The 6th Biennial meeting of Asian Breast Cancer Society, Hong Kong, 2007, p 110.
- T.Y Loo, J Chen*. W.C Chow. A 3-year Prospective Study in Monitoring Bone Mineral Density of Mandible in 180 Fully Edentulous Patients after chemotherapy, The 6th Biennial meeting of Asian Breast Cancer Society, Hong Kong, 2007, p 108.
- J Chen*. WDY' Academically Conference, Breast cancer treatment strategy in Chinese Medicine, 2007.
- J Chen*, T Loo, W Chou. Juzen-taiho-to enhances immune activity in vitro and minimizes cyto-toxicity in vivo, the 6th Biennial meeting of Asian Breast Cancer Society, 2007.
- J Chen*, T.Y Loo. The therapeutic effect of Shugansanjie Tang on human breast tumor tissue, The Third Annual Conference of the Organization for Oncology and Metastasis Research, Japan, 2006.
- J Chen*, Y Tong, T Wong. Diosgenin against myocardial injury induced by ischemia and reperfusion in rats, Fifth CGCM, 2006.
- T Wang, J Chen*, H Huang, J Shen, D Yang, D Wang. Protective effects of Diosgenin against myocardial in jury induced by ischemia and reperfusion in rat. Critical Care Medicine 2006.
- J Chen*, T.M Wong. Protective effects of Diosgenin against myocardial injury induced by ischemia and reperfusion, 2006 international symposium for traditional Chinese medicine and integration of traditional Chinese & western medicine, Hong Kong, 2006.
- J Chen*, F Han. Becoming easy to learn Chinese Medicine Prescriptions, AMEE Association for Medical Education in Europe, 2006.
* As correspondence or first author.
2. Patents (publication, application, approved or submitted)
- A METHOD OF MAKING EXTRACTS OF SPATHOLOBUS SUBERECTUS DUNN (SSP), COMPOSTIONS THEREOF AND METHOD AGAINST VIRAL DISEASES application no. 63/319,940.2022.3
- 陳建萍,姜洋,劉青青,張鋒,賈雷,文毅,王志宇,彭芙。雞血藤提取物的提取方法,雞血藤提取物及其用途,中華人民共和國國家知識產權局,已經受理,授權日:2022年1月14日,公開號:CN113925890A。
- 一种异甘草素白蛋白纳米制剂的制备及应用CN(submit in 2021)
- 異甘草素的新用途20181036347.7 CN(submit in 2020)
- 鸡血藤提取物的提取方法、鸡血藤提取物及其用途(202010607628 .3 )
- 获得欧洲专利:鸡血藤的单体成份抗病毒的相关研究
- 一種具有減毒功效的組合物及其製備方法和應用.Patent (application) No: 2016102214254 China. PI. Approved the patent 2021
- Use of isoflavones for the treatment of retro viral infection. Patent No: 14871042.9 European Patent Office, 2016 , 授權:EP3082799B1
- 一種預防或治療乳腺癌的外用製劑.Patent (application) No: 2015101806429. In China PI,2015.
- Use of isoflavones for the treatment of retro viral infection. PCT/cn2014/09408(US patent) Co-I. 2015.
- 一種治療愛滋病的地榆提取物及其製備方法.Patent No:20131026876,In China PI, 2013
- 雞血藤提取物及其運用和異甘草素的新用途.Patent No:61/917175,in China (PI,2013)
- 一種治療腫瘤的中藥組合物. Patent No: 201210019695.9 China(PI, 2013)
- International class: A61K35/78, Authorized Date: July.21th, 2004, State Intellectual Property of P.R.China. Patent No: ZL 001 14056.602134382.9, Internal Class: A01K35/78. China. PI, 2004.
- Extraction and Purification Method of Shan Daogan Compounds and use from Plants; Inventor: China Patent No. ZL00114056.6 ( PI, 2002)
3. Other contributions
- A multimedia CD-ROM about the prescription for our students using.
- Abuse of Wushi Powder in Old China: Archival Analysis using Qualitative Approach (theses of my student WS Yeung in 2009)
- Ellagic Acid Can Exert Anti-angiogenesis Effects in Breast Cancer (theses of my student N Wang in 2011)
- Consultancy service offered to: (1) Food health in Vocational Training Council HK in 2003-2011; (2) Specialist of Chinese Medicine Council Guangzhou, China.2011; (3) National Science Fund of China in 2005-2008; (4) Hong Kong Council for Academic Accreditation 2006-2011; (5) Chinese Medicine Council of HK
4. Editorship, Invited lecture and keynote speeches
A. Editorship
- Editor:
- Textbook (TCM Culture 中醫藥文化學) in China
- Textbook (TCM Prescription) in Hong Kong
- Editorship:
- Evidence-Based Complementary and Alternative Medicine Chinese Medicine.
- Global Traditional Chinese Medicine.
B. Reviewer
- As a reviewer and evaluation experts for NSFC (until now).
- As a reviewer for peer journals of:
- ╴Analytical Chemical Acta, and Global Traditional Chinese medicine.
- ╴Global Traditional Chinese Medicine.
- ╴International Journal of Health Science and Well Being
- ╴Natural Science
- ╴Cancer Therapy
- ╴Oncotarget
- ╴Tumor biology
- ╴Chinese Journal of Integrative Medicine
- ╴Carcinogenesis
- ╴African Journal of Biotechnology
C. Invited / plenary lecture / keynoted speeches in international region
1) Invited lecture / keynote speeches
- Chinese Medicine Against Novel COVID-19: more than 7 times lecture for local people and TCM Doctors( 2021-2022
- A Pioneering to Develop Anti-COVID-19 Medicines in TCM area 2022
- Say caulis spatholobi in genera. 6th ICETCM( international conference on the modernization of TCM) 2019-10-22 in Chengdu.
- Evidence-based Medicine Discussion on Breast Cancer with Emotional Problems and View of Traditional Chinese Medicine. 6th ICETCM( international conference on the modernization of TCM) 2019-10-22, in Chengdu.
- Research & developing on national medicine industrialization. 6th ICETCM( international conference on the modernization of TCM), 2019-10-21, in Chengdu.
- The wisdom of eating- Medicine and food are homologous to treat diseases. 6th ICETCM(international conference on the modernization of TCM) . 2019-10-21, in Chengdu.
- Health by yourself. No2 international health conference. 2019-9-29 Hong Kong.
- Emotion induces breast cancer growth. 2019-7 in London, U K.
- Metabolomics study of ethanol extract from Caulis Spatholobi(EECS)on weight loss via energy metabolism. Traditional and Alternative Medicine. 2019-6 in Belin, Germany.
- When TCM meet breast cancer .香港中醫骨傷學院. 2019-5-26
- 話說雞血藤, 中醫藥轉換醫學講座.2019-4-30
- 關愛乳房—做一個健康美麗的女人.國際中醫美容高峰論壇.2019-4,13
- 林毅“從六鬱治乳”學術思想的傳承全國名中醫林毅學術思想傳承學習班2019-3-24
- When Chinese medicine (仲景學術) meet Breast cancer.2018-12-9 in HKBU.
- Relationship between Constitution of TCM and Breast cancer in Guangzhou No 1 integrated traditional and Western medicine in Breast disease 2016-3-26 in Guangzhou China.
- A Cross-Institution Online Problem Based Learning in Chinese Medicine Education. Asia Pacific Education and Communication Technology 2016; 2 in Austria;
- Effects of 5-element music on female patients of breast cancer with mental disorders after surgery. 9 th PDY international symposium On TCM. Dec 04 2015 HK.
- The Inhibitory Effect of Isoliquiritigenin/Spatholobus Suberectus on Breast Cancer Metastasis---- a Process Modulated by the Up-expression of miR-374a and Down-expression of miR-200c. CGCM, (08 / 2015) in Canada.
- J Chen, “The strategy of TCM for Breast” Nov29 2015, international health conference in Hong Kong
- The international processes of TCM sports & health. Nov29 2014, international health conference in Guangzhou
- When Chinese Medicine meet Breast cancer. The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research (15-16th, Nov2014, HKU)
- Chinese medicine idea of depress on Breast cancer. The conference of Professor Lin-Yi excerpted of Breast cancer.Nov.2014in Guiling.
- Qigong promotion recover of breast cancer disease. the Clinical Investigation (Cancer, Liver Disease and Inflammation). CGCM2014 Beijing.
- ISL anti-metastasis in breast cancer. OOTR Translational Oncology Session at Israel on June 19, 2014.
- Science promotion of TCM in University of HK. 2014 July science promotion of TCM in international health conference in Chongqing.
- Association of Emotional Disorders with the Physical Exercising Habits among Hospital Discharged Breast Cancer Patients in Hong Kong. 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM Graz, Austria, August 27-29) 2013.
- LDH-A, a potential molecular target for cancer. 4th international Chinese Medicine conference in Chengdu (2013-10-26-27)
- LDH-A, a potential molecular target for cancer therapy and development of specific Inhibitors from Spatholobus suberectus. 2012 conference of Asia Oceania research Organisation on Genital infection and Neoplasia (13-15July 2012).
- Using association rules mining to explore compatibility of Chinese medicinal formulae (prescription) which treat and prevent breast cancer recurrence and metastasis. The12th National Traditional Chinese Medicine, Integrative Medicine of Breast Disease in Beijing 2011(28-30th Oct)
- Relationship between liver blood deficiency and female breast cancer in the view of the TCM. The 49th World Congress of Integrated Medicine held in Kuala Lumpur, Malaysia, 2011.
- The International Chinese Medicine Congress and the 11th National Traditional Chinese Medicine, Integrative Medicine of Breast Disease in Guilin China, 2009.
- Juzen-taiho-to enhance immune activity in vitro and minimize cyto-toxicity in vivo. The 6th Biennial meeting of Asian Breast Cancer Society, Hong Kong, 2007.
2) Panelist and Chairman in section conference
- 6th international TCM conference 2019-10-22, in Chengdu.
- CGCM Meeting of the Consortium for Globalization of Chinese Medicine, Panelist,2019
- CGCM Meeting of the Consortium for Globalization of Chinese Medicine, Panelist,2017
- CGCM Meeting of the Consortium for Globalization of Chinese Medicine, Panelist,2016
- CGCM Meeting of the Consortium for Globalization of Chinese Medicine, Panelist,2015
- CGCM Meeting of the Consortium for Globalization of Chinese Medicine, Panelist, 2014
- The Research and development of Chinese Medicine, The Committee on Research and development of Chinese Medicine in Hong Kong University of Hong Kong, December 12-13, 2012.
- The 1st Symposium of innovative Chinese medicine & The 2nd Doctoral Forum on Chinese medical Sciences, Macau, December 6-8, 2012.
- The 7th Pong Ding Yuen Symposium on Traditional Chinese Medicine, Hong Kong, December 1-3, 2012.
- The 12th Meeting of the Consortium for Globalization of Chinese Medicine, Panelist, Session of Biological Activities and Mechanism Study II (Metabolic, Neural Diseases and Aging Process), Graz, August 25-29, 2013.
- The 8th Pong Ding Yuen Symposium on Traditional Chinese Medicine, Hong Kong, December 1-3, 2013.