Project Period: 1/10/2023 to 30/9/2026

Elucidating roles of adaptor protein APPL2 in inhibiting adult neurogenesis via affecting mitochondrial function, redox signaling and mitochondrial dynamics in ischemic stroke with hyperglycemia

Project Period: 1/10/2020 to 30/9/2023

Elucidating the roles of hypochlorous acid (HOCl) in mediating hemorrhage transformation (HT) in ischemic stroke with delayed thrombolytic therapy and its application for therapeutic approach with Acteoside

Project Period: 1/9/2020 to 28/2/2025

Artificial intelligence recognitions for traditional Chinese medicine pulse patterns and its correlation study with body constitution types in healthy human subjects

Project Period: 1/9/2017 to 1/9/2020

Exploring Molecular Targets for Drug Discovery to Preventing Hyperglycemia-mediated Hemorrhagic transformation in Ischemic Stroke: Sodium Danshensu (SDSS) as an Example

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Project Period: 1/1/2022 to 31/12/2024

Transcutaneous electrical acupoint stimulation and dense cranial electroacupuncture stimulation for psychiatric sequelae and related biomarkers in women victims of domestic violence: a randomized controlled trial

Project Period: 1/9/2020 to 31/8/2023

Combining acupuncture and acupressure for community-dwelling elderly with dementia: an assessor-blinded, randomized controlled trial

Project Period: 1/5/2019 to 27/7/2024

The effect of acupuncture for insomnia in breast cancer patients undergoing chemotherapy: a randomized, sham-controlled trial

Project Period: 1/9/2017 to 1/9/2020

Resveratrol and ginsenoside Rg1 combination protects against chemotherapy-induced cognitive impairment: synergistic mechanisms of cytokine-modulating and anti-neurotoxic actions

Project Period: 1/10/2017 to 1/8/2020

A double-blind, randomised,placebo-controlled trial of berberine as an adjuvant to treat antipsychotic-induced metabolic syndrome in patients with schizophrenia spectrum disorders

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Project Period: 1/1/2020 to 30/6/2023

Chinese medicine pentacyclic triterpene celastrol ameliorates inflammation, metabolic dysfunctions and insulin resistance in diet-induced obesity via covalently modifying endoplasmic reticulum chaperone GRP78

Project Period: 1/4/2019 to 31/3/2022

Pharmacological induction of pro-resolving macrophages for suppressing cardiac fibrosis in experimental myocardial infarction

Project Period: 1/1/2018 to 31/12/2021

Arachidonic acid metabolite (15-keto-PGF2α) regulates macrophage M1/M2 polarization against myocardial ischemia reperfusion injury via covalent conjugation with glycolytic enzyme PKM2

Project Period: 1/1/2018 to 1/1/2021

Plant-derived celastrol ameliorates metabolic dysfunctions, oxidative stress and inflammation in diet-induced obesity via disrupting the cross-talk between PKM2, HIF-1α and IL-1β

Project Period: 1/1/2017 to 1/1/2020

ω-Alkynyl arachidonic acid induces anti-inflammatory M2 polarization of macrophages in acute myocardial infarction via regulating the cross-talk between PKM2, iNOS and HIF-1α

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Project Period: 1/1/2017 to 31/12/2020

The latent TGF-β protects against diabetic kidney disease via GARP-latent TGF-β mediated anti-inflammation: mechanism and therapeutic potential

Project Period: 1/9/2020 to 30/4/2024

The adjunctive effect of acupuncture for advanced cancer patients in a collaborative model of palliative care: a three-arm pragmatic randomized trial

Project Period: 1/7/2019 to 31/12/2022

Blockade of Smad3 attenuates diabetic nephropathy via suppressing C-reactive protein-mediated NLPR3 inflammasome activation

Project Period: 1/12/2020 to 30/11/2021

An evidence-based research and promotion of Chinese Medicine for COVID-19

Project Period: 1/1/2024 to 31/12/2026

Mettl3-mediated m6A modification of Ndrg1 promotes acute kidney injury (AKI) sensitivity in diabetic nephropathy

Project Period: 1/1/2025 to 31/12/2027

Adiponectin attenuates the susceptibility of the kidney to acute injury under diabesity via suppressing NLRP3-mediated pyroptosis

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Project Period: 1/1/2024 to 31/12/2026

Role of STING/IFN-I axis in the pathogenesis of primary Sjogren’s syndrome

Project Period: 15/4/2024 to 14/4/2026

The Therapeutic Potential of Immunomodulatory Compounds from Astragali Radix on Primary Sjogren’s Syndrome

Project Period: 20/7/2023 to 19/7/2025

Calycosin ameliorates experimental Sjogren’s syndrome via inhibiting effector T cell response

Project Period: 1/1/2022 to 31/12/2024

Role of Caveolin-1 in regulating T cell responses in primary Sjogren’s syndrome

Project Period: 1/9/2022 to 31/8/2024

Targeting peroxisome proliferator-activated receptors in the treatment of Sjögren’s syndrome

Project Period: 1/1/2021 to 31/12/2023

Novel Therapeutic Strategy for Sjogren’s Syndrome: Targeting Myeloid-Derived Suppressor Cells

Project Period: 15/4/2020 to 15/4/2021

Heat-cooling Chinese herbs in treating chronic hepatitis B patients comparing with antiviral therapy: A systematic review and network meta-analysis

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Project Period: 24/10/2023 to 23/9/2024

The Study of CP1-CHM Regulating Lipid Metabolism in Obese Patients through Gut Microbiome

Project Period: 1/4/2018 to 31/3/2020

Investigation on the effect of berberine on improvement of diabetic retinopathy in insulin-treated diabetic mellitus

Project Period: 1/4/2021 to 31/3/2022

Development of training platform of the toxicity, safety and proper application of Chinese Medicine for Chinese Medicine-related practitioners

Project Period: 1/8/2020 to 31/7/2022

中藥炮制傳統工藝 ""九蒸九晒""的調研,優化及評價一一以根莖類中樂何首鳥,黃精及地黃為例

Project Period: 1/12/2021 to 31/11/2024

Investigation of the effect of berberine to overcome sorafenib resistance in human hepatocellular carcinoma via suppressing Warburg effect

Project Period: 1/12/2021 to 31/11/2025

Hypoxia-induced FABP4 in myeloid-derived suppressor cells as a novel target for managing the recurrence of hepatocellular carcinoma after surgical resection

Project Period: 1/2/2023 to 31/1/2025

The Study of CP1-CHM Regulating Lipid Metabolism in Obese Patients through Gut Microbiome

Project Period: 1/11/2024 to 31/10/2027

Batatasin I, an active component from tonic Chinese medicine Dioscoreae Rhizoma, mitigates inflammation-related muscle and adipose wasting in pancreatic cancer-associated cachexia

Project Period: 1/12/2024 to 31/11/2025

A randomized, waitlist-controlled clinical study on the efficacy and safety of Lingzhi-containing dietary supplement CP003 on chronic fatigue and post-COVID fatigue

Project Period: 1/1/2025 to 31/12/2027

Berberine potentiates anti-PD-1 efficacy in hepatocellular carcinoma

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Project Period: 1/10/2024 to 30/9/2026

Exploring the Metabolic Regulatory Role of HDCA in Autoimmune Uveitis

Project Period: 1/2/2024 to 31/1/2025

Dysregulated Host - Gut Microbiota Co-Metabolism in Metabolic Associated Fatty Liver Disease

Project Period: 1/9/2022 to 28/2/2025

Verification of the beneficial effect and safe use of combined FOLFOX and Patriniae Herba extract in colorectal cancer Proof-of-concept for clinical use

Project Period: 1/4/2018 to 31/3/2020

Transcriptomic profiling of the gene networks reveals the roles of BDNF and RragA in the anti-depressive and analgesic activities of Chinese medicine Puerarin

Project Period: 1/7/2020 to 30/6/2023

RNA-Seq transcriptome profiling of Rraga-knock-in mouse brains for the mechanisms underlying the anti-depressive activity of Chinese medicine puerarin

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