廣東話、普通話和英語

中文和英文

研究基金

研究獲頒獎項

期刊編委

代表性論文

1. Wu M*, Yu S*, Chen Y, Meng W, Chen H, He J, Shen J#, Lin X#. Acteoside promotes B cell-derived IL-10 production and ameliorates autoimmunity. Journal of Leukocyte Biology (DOI: 10.1002/JLB.3MA0422-510R, Impact factor: 6.0)  
2. Wang X, Lin X, Zheng Z, Lu B, Wang J, Tan AH, Zhao M, Loh JT, Ng SW, Chen Q, Xiao F, Huang E1, Ko KH, Huang Z, Li J, Kok KH, Lu G, Liu X, Lam KP, Liu W, Zhang Y, Yuen KY, Mak TW, Lu L. Host- derived lipids orchestrate pulmonary γδ T cell response to provide early protection against influenza virus infection. Nature Communications. 2021, 12: 1914. (Impact factor: 17.69)
3. Yu H, Wu W, Lin X and Feng Y. Polysaccharide-Based Nanomaterials for Ocular Drug Delivery: A Perspective. Frontiers in Bioengineering and Biotechnology. 2020, 8:601246. (Impact factor: 6.06)
4. Lin X, Wang X, Xiao F, Ma K, Liu L, Xu D, Wang F, Shi X, Zhao Y, Liu D, Lu L. IL-10-producing regulatory B cells restrain the T follicular helper cell response in primary Sjögren’s syndrome. Cellular & Molecular Immunology. 2019, 16: 921-931. (Impact factor: 22.09)
5. Wang X, Ye C, Lin X, Ma K, Xiao F, Li L, Lu L. New insights into the significance of the BCR repertoire in B-1 cell development and function. Cellular & Molecular Immunology. 2019, 16(9): 772-773. (Impact factor: 22.09)
6. Ma K, Wang X, Shi X, Lin X, Xiao F, Ma X, Liu D, Lu L. The expanding functional diversity of plasma cells in immunity and inflammation. Cellular & Molecular Immunology. 2019, doi: 10.1038/s41423-019-0308-z (Impact factor: 27.97)
7. Tian J, Rui K, Hong Y, Wang X, Xiao F, Lin X, Ma J, Guo H, Xu H, Ma K, Xu D, Liu D, Zhao Y, Lu L, Wang S. Increased GITRL Impairs the Function of Myeloid-Derived Suppressor Cells and Exacerbates Primary Sjögren Syndrome. The Journal of Immunology. 2019, 15;202(6):1693-1703. (Impact factor: 5.42)
8. Guggino G*, Lin X* (co-first author), Rizzo A, Xiao F, Saieva L, Liberto D, Candore G, Ruscitti P, Cipriani P, Giacomelli R, Dieli F, Alessandro R, Triolo G, #Lu L, #Francesco C. Interleukin-25 Axis Is Involved in the Pathogenesis of Human Primary and Experimental Murine Sjogren's Syndrome. Arthritis & Rheumatology. 2018, 70(8):1265-1275. (Impact factor: 15.48)
9. Ma K, Li J, Wang X, Lin X, Du W, Yang X, Mou F, Fang Y, Zhao Y, Hong X, Chan KW, Zhang X, Liu D, Sun L, Lu L. TLR4(+)CXCR4(+) plasma cells drive nephritis development in systemic lupus erythematosus. Annals of the Rheumatic Diseases. 2018, 77:1498-1506. (Impact factor: 19.10)
10. Fu W, Liu X, Lin X, Feng H, Sun L, Li S, Chen H, Tang H, Lu L, Jin W, Dong C. Deficiency in T follicular regulatory cells promotes autoimmunity. Journal of Experimental Medicine. 2018; 215(3):815-825. (Impact factor: 17.57).
11. Rui K*, Lin X* (co-first author), Tian J, Wang X, Sun L, Hong X, Liu D, Wang S, Lu L. Ecto-mesenchymal stem cells: a new player for immune regulation and cell therapy. Cellular & Molecular Immunology. 2018, 15(1):82-84. (Impact factor: 22.09)
12. Xiao F, Lin X, Tian J, Wang X, Chen Q, Rui K, Ma J, Wang S, Wang Q, Wang X, Liu D, Sun L, Lu L. Proteasome Inhibition Suppresses Th17 cell Generation and Ameliorates Autoimmune Development in Sjögren’s Syndrome. Cellular & Molecular Immunology. 2017, 14: 924–934. (Impact factor: 22.09)
13. Lin X, Rui K, Deng J, Tian J, Wang X, Wang S, Ko KH, Jiao Z, Chan VS, Lau CS, Cao X, Lu L. Th17 cells play a critical role in the development of experimental Sjögren's syndrome. Annals of the Rheumatic Diseases. 2015, 74(6):1302-10. (Impact factor: 27.97)
14. Rui K, Zhang Z, Tian J, Lin X, Wang X, Ma J, Tang X, Xu H, Lu L, Wang S. Olfactory ecto-mesenchymal stem cells possess immunoregulatory function and suppress autoimmune arthritis. Cellular & Molecular Immunology, 2016, 13(3):401-8. (Impact factor: 22.09)
15. Lin X, Liu J, Chung W, Sze SC, Li H, Lao L, Zhang Y. Polysaccharides of Dendrobium officinale Induce Aquaporin 5 Translocation by Activating M3 Muscarinic Receptors. Planta medica. 2015, 81(2):130-137. (Impact factor: 3.00)
16. Lin X, Tian J, Rui K, Ma KY, Ko KH, Wang S, Lu L. The role of T helper 17 cell subsets in Sjögren's syndrome: similarities and differences between mouse model and humans. Annals of the Rheumatic Diseases.2014, 73(7):e43. (Impact factor: 27.97)
17. Lin X, Shaw PC, Sze CW, Tong Y, Zhang YB. Polysaccharides of Dendrobium Officinale inhibit TNF-α induced apoptosis in A-253 cell line. Inflammation Research. 2013 63 (3): 313-24 (Impact factor: 6.98)
18. Lin X, Shaw PC, Sze SC, Tong Y, Zhang Y. Dendrobium officinale polysaccharides ameliorate the abnormality of aquaporin 5, pro-inflammatory cytokines and inhibit apoptosis in the experimental Sjögren's syndrome mice. International Immunopharmacology. 2011, 11 (12): 2025-32. (Impact factor: 5.71)
19. Lin X, Song JX, Shaw PC, Ng TB, Sze CW, Tong Y, Lee KF, Zhang KY. An autoimmunized mouse model recapitulates key features in the pathogenesis of Sjögren's syndrome. International Immunology. 2011 23 (10): 613-624. (Impact factor: 5.07)
20. Song JX, Lin X, Wong RNS, Sze SCW, Tong Y, Shaw PC, Zhang YB. Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta‐amyloid and homocysteine neurotoxicity in PC12 cells. Phytotherapy Research. 2011, 25 (3), 435-443 (Impact factor: 6.38)

其他論文

1. Weifeng Wu, Xiao R Huang, Yongke You, Liang Xue, Xiao-Jing Wang, Xiaoming Meng, Xiang Lin, Jiangang Shen, Xueqing Yu, Hui-Yao Lan, Haiyong Chen. Latent TGF-b1 protects against diabetic kidney disease via Arkadia/Smad7 signaling. Int J Biol Sci 2021, 19;17(13):3583-3594. (Impact factor: 10.75; Q1)
2. Fraide A Ganotice, Kelvin Kai Hin Fan, Zoe Lai Han Ng, Francis Hang Sang Tsoi, Abraham Ka Chung Wai, Alan Worsley, Xiang Lin, George L Tipoe. The short version of students' perceptions of interprofessional clinical education-revised (SPICE-R3): a confirmatory factor analysis. Journal of Interprofessional Care (Impact factor: 2.66; Q2)
3. Shayi Wu*, Miao Chen*, Jiao Huang, Feifei Zhang, Zhaojie Lv, Yongxu Jia,2 Yu-Zhu Cui, Liang-Zhan Sun, Ying Wang, , Ying Tang, Krista R. Verhoeft, Yan Li, Yanru Qin, Xiang Lin, Xin-Yuan Guan#, Ka-On Lam#. ORAI2 Promotes Gastric Cancer Tumorigenicity and Metastasis Through PI3K/Akt Signaling and MAPK-dependent Focal Adhesion Disassembly. Cancer Research. 2020 DOI: 10.1158/0008-5472.CAN-20-0049. (Impact factor: 13.31 Q1)
4. Zhao J Lyu, Ying Wang, Jin L Huang, Miao Chen, Sha Y Wu, Qian Yan, Yu Zhang, Ying Tang, Chen Jiang, Lei Li, Yi Z Jia, Yu C Liu, Hong B Mei, Feng Wang, Ren H Li, Ya C Chen, Xiang Lin, Zhi M Cai, Xin Y Guan. Recurrent ZNF83-E293V Mutation Promotes Bladder Cancer Progression through the NF-κB Pathway via Transcriptional Dysregulation of S100A8. Molecular Therapy. 2020 S1525-0016(20)30461-5. (Impact factor: 12.91; Q1)
5. Chu H, Zhou J, Wong BH, Li C, Cheng ZS, Lin X, Poon VK, Sun T, Lau CC, Chan JF, To KK, Chan KH, Lu L, Zheng BJ, Yuen KY. Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response. Virology. 2014, 454-455:197-205. (Impact factor: 3.51; Q2)

研討會文章

1. Blocking of CD103+ tissue resident memory t cells (TRM) as a therapeutic strategy in Sjogren’s syndrome. Proceeding/Conference: Annals of the Rheumatic Diseases
2. Novel function of IL-17E in the autoimmune pathogenesis of experimental Sjogren´s syndrome Proceeding/Conference: European Journal of Immunology
3. Polysaccharides from dendrobium officinale ameliorate murine Sjögren's syndrome development via modulating immune responses. Proceeding/Conference:7th Federation of Immunological Societies of Asia-Oceania Congress (FIMSA 2018)
4. A Critical Role of Th17 Cells in the Development of Murine Sjogeren’s Syndrome. Proceeding/Conference: Journal of Immunology

著作 \書籍

1. Yu S, Wu M, Feng Y, Shen J, Lu L and Lin X. Detection of T follicular helper cells and T follicular regulatory cells in experimental Sjögren’s syndrome. Methods in Molecular Biology. Humana Press, New York, NY
2. Lin X, Lu L. (2019) Chapter 13: B cell-mediated autoimmune diseases. B Cells in Immunity and Tolerance. Advances in Experimental Medicine and Biology. Springer Nature International Publishing AG. (United States)
3. Lin X, Deng J, Lu L. (2014) IL-10 Detection in Murine B Cells: Pros and Cons of the Different Techniques. In: Vitale G., Mion F. (eds) Regulatory B Cells. Methods in Molecular Biology. Humana Press, New York, NY
4. Lin X, Zhang Kalin YB (2009) Chapter 28-30, Basic and Clinical Toxicology of Chinese Medicine. Commercial Press (HK) Ltd. (Chinese).